Literature DB >> 15367230

Living donor liver transplantation with left liver graft.

Michele Masetti1, Antonio Siniscalchi, Lesley De Pietri, Vanessa Braglia, Fabrizio Benedetto, Nicola Di Cautero, Bruno Begliomini, Antonio Romano, Charles M Miller, Giovanni Ramacciato, Antonio D Pinna.   

Abstract

Small-for-size syndrome in LDLT is associated with graft exposure to excessive portal perfusion. Prevention of graft overperfusion in LDLT can be achieved through intraoperative modulation of portal graft inflow. We report a successful LDLT utilising the left lobe with a GV/SLV of only 20%. A 43 year-old patient underwent to LDLT at our institution. During the anhepatic phase a porto-systemic shunt utilizing an interposition vein graft anastomosed between the right portal branch and the right hepatic vein was performed. After graft reperfusion splenectomy was also performed. Portal vein pressure, portal vein flow and hepatic artery flow were recorded. A decrease of portal vein pressure and flow was achieved, and the shunt was left in place. The recipient post-operative course was characterized by good graft function. Small-for-size syndrome by graft overperfusion can be successfully prevented by utilizing inflow modulation of the transplanted graft. This strategy can permit the use of left lobe in adult-to-adult living donor liver transplantation.

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Year:  2004        PMID: 15367230     DOI: 10.1111/j.1600-6143.2004.00548.x

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  11 in total

1.  Increasing donor body weight to prevent small-for-size syndrome in living donor liver transplantation.

Authors:  Chinsu Liu; Rheun-Chuan Lee; Che-Chuan Loong; Cheng-Yuan Hsia; Yi-Chen Yeh; See-Ying Chiou
Journal:  World J Surg       Date:  2010-10       Impact factor: 3.352

2.  Splenectomy enhances the anti-fibrotic effect of bone marrow cell infusion and improves liver function in cirrhotic mice and patients.

Authors:  Takuya Iwamoto; Shuji Terai; Yuko Mizunaga; Naoki Yamamoto; Kaoru Omori; Koichi Uchida; Takahiro Yamasaki; Yasuhiko Fujii; Hiroshi Nishina; Isao Sakaida
Journal:  J Gastroenterol       Date:  2011-11-09       Impact factor: 7.527

Review 3.  Liver function impairment in liver transplantation and after extended hepatectomy.

Authors:  Matteo Serenari; Matteo Cescon; Alessandro Cucchetti; Antonio Daniele Pinna
Journal:  World J Gastroenterol       Date:  2013-11-28       Impact factor: 5.742

Review 4.  Portosystemic Shunts for "Too Small-for-Size Syndrome" After Liver Transplantation: A Systematic Review.

Authors:  Erdem Kinaci; Cuneyt Kayaalp
Journal:  World J Surg       Date:  2016-08       Impact factor: 3.352

5.  How to handle a huge portosystemic shunt in adult living donor liver transplantation with a small-for-size graft: report of a case.

Authors:  Yasumasa Shirouzu; Yuki Ohya; Yukika Tsukamoto; Hidekazu Yamamoto; Kwang-Jong Lee; Hideaki Okajima; Katsuhiro Asonuma; Yukihiro Inomata
Journal:  Surg Today       Date:  2009-06-28       Impact factor: 2.549

Review 6.  Small-for-size syndrome in living-donor liver transplantation using a left lobe graft.

Authors:  Masahiko Taniguchi; Tsuyoshi Shimamura; Satoru Todo; Hiroyuki Furukawa
Journal:  Surg Today       Date:  2014-06-05       Impact factor: 2.549

7.  Early Graft Dysfunction in Living Donor Liver Transplantation and the Small for Size Syndrome.

Authors:  Jay A Graham; Benjamin Samstein; Jean C Emond
Journal:  Curr Transplant Rep       Date:  2014-03

8.  The outcomes of pediatric living donor liver transplantation using small-for-size grafts: experience of a single institute.

Authors:  Naoya Yamada; Yukihiro Sanada; Yuta Hirata; Noriki Okada; Yoshiyuki Ihara; Hideki Sasanuma; Taizen Urahashi; Yasunaru Sakuma; Yoshikazu Yasuda; Koichi Mizuta
Journal:  Pediatr Surg Int       Date:  2016-01-19       Impact factor: 1.827

Review 9.  Current concept of small-for-size grafts in living donor liver transplantation.

Authors:  Toru Ikegami; Mitsuo Shimada; Satoru Imura; Yusuke Arakawa; Akira Nii; Yuji Morine; Hirofumi Kanemura
Journal:  Surg Today       Date:  2008-10-29       Impact factor: 2.549

10.  Historical perspective of living donor liver transplantation.

Authors:  See Ching Chan; Sheung Tat Fan
Journal:  World J Gastroenterol       Date:  2008-01-07       Impact factor: 5.742

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