| Literature DB >> 15366708 |
Roberto Buccione1, James D Orth, Mark A McNiven.
Abstract
The plasma membrane of many motile cells undergoes highly regulated protrusions and invaginations that support the formation of podosomes, invadopodia and circular dorsal ruffles. Although they are similar in appearance and in their formation--which is mediated by a highly conserved actin-membrane apparatus--these transient surface membrane distortions are distinct. Their function is to help the cell as it migrates, attaches and invades.Mesh：
Year: 2004 PMID： 15366708 DOI： 10.1038/nrm1436
Source DB: PubMed Journal: Nat Rev Mol Cell Biol ISSN： 1471-0072 Impact factor: 94.444