Literature DB >> 15365147

Thalamic deep brain stimulation activates the cerebellothalamocortical pathway.

G F Molnar1, A Sailer, C A Gunraj, A E Lang, A M Lozano, R Chen.   

Abstract

To investigate the mechanism of action of deep brain stimulation (DBS), the authors studied the effects of thalamic DBS on the cerebellothalamocortical (CTC) pathway. With DBS turned off, excitability of the CTC pathway was reduced. Turning DBS on resulted in facilitation of the CTC pathway. Therefore, thalamic DBS appears to activate rather than inhibit the target area.

Mesh：

Year:  2004        PMID： 15365147     DOI： 10.1212/01.wnl.0000137419.85535.c7

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  16 in total

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