David H Abramson1, Mark R Melson, Camille Servodidio. 1. Ophthalmology Oncology Service, Departments of Surgery, Radiation Oncology, and Pediatrics, Memorial Sloan-Kettering Cancer Center, New York, NY. ICANCERMD@aol.com
Abstract
OBJECTIVE: To describe the visual field defects in retinoblastoma survivors and relate those defects to characteristics such as tumor size, tumor location, and treatment modality. METHODS: Thirty-one patients treated for retinoblastoma were included in this study. Humphrey visual fields were determined in 33 eyes. RESULTS: Twenty-seven patients (29 eyes, 68 tumors) had sufficient diagnosis and treatment data available for further analysis. Twenty-six of the 27 patients had both absolute and relative visual field defects. Four types of visual field defects were observed and correlated with location of the tumor and therapy to the individual tumors: (1) no residual defect, (2) absolute scotoma, (3) arcuate and sector scotoma, and (4) "pseudo"-visual field defects caused by relative enophthalmos resulting from radiation. CONCLUSIONS: Patients with retinoblastoma demonstrate a variety of long-term visual field defects after treatment for their intraocular disease. Characteristics that determine the size and type of defects are tumor size, tumor location, and treatment method.
OBJECTIVE: To describe the visual field defects in retinoblastoma survivors and relate those defects to characteristics such as tumor size, tumor location, and treatment modality. METHODS: Thirty-one patients treated for retinoblastoma were included in this study. Humphrey visual fields were determined in 33 eyes. RESULTS: Twenty-seven patients (29 eyes, 68 tumors) had sufficient diagnosis and treatment data available for further analysis. Twenty-six of the 27 patients had both absolute and relative visual field defects. Four types of visual field defects were observed and correlated with location of the tumor and therapy to the individual tumors: (1) no residual defect, (2) absolute scotoma, (3) arcuate and sector scotoma, and (4) "pseudo"-visual field defects caused by relative enophthalmos resulting from radiation. CONCLUSIONS:Patients with retinoblastoma demonstrate a variety of long-term visual field defects after treatment for their intraocular disease. Characteristics that determine the size and type of defects are tumor size, tumor location, and treatment method.
Authors: Danielle Novetsky Friedman; Joanne F Chou; Kevin C Oeffinger; Ruth A Kleinerman; Jennifer S Ford; Charles A Sklar; Yuelin Li; Mary S McCabe; Leslie L Robison; Brian P Marr; David H Abramson; Ira J Dunkel Journal: Cancer Date: 2016-01-11 Impact factor: 6.860
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Authors: Scott M Barb; Carlos Rodriguez-Galindo; Matthew W Wilson; Nicholas S Phillips; Ping Zou; Matthew A Scoggins; Yimei Li; Ibrahim Qaddoumi; Kathleen J Helton; George Bikhazi; Barrett G Haik; Robert J Ogg Journal: Invest Ophthalmol Vis Sci Date: 2011-04-20 Impact factor: 4.799
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Authors: Elyssa Y Wong; Liya Xu; Lishuang Shen; Mary E Kim; Ashley Polski; Rishvanth K Prabakar; Rachana Shah; Rima Jubran; Jonathan W Kim; Jaclyn A Biegel; Xiaowu Gai; Peter Kuhn; James Hicks; Jesse L Berry Journal: NPJ Precis Oncol Date: 2021-07-27