| Literature DB >> 15359733 |
Irene Messana1, Tiziana Cabras, Rosanna Inzitari, Alessandro Lupi, Cecilia Zuppi, Chiara Olmi, Maria Benedetta Fadda, Massimo Cordaro, Bruno Giardina, Massimo Castagnola.
Abstract
Thirteen samples of human normal whole saliva were analyzed by RP-HPLC-ESI-MS and MALDI-TOF-MS to investigate the basic proline-rich protein complex. Between known basic-PRPs the P-B, P-C (or IB-8b), P-D (or IB-5), P-E (or IB-9), P-F (or IB-8c), P-H (or IB-4), IB-6, II-2, IB-1, and IB-8a glucosylated were identified, whereas the II-1, IB-7, PA, and D1-A peptides were not detected. Some detected masses not attributable to known basic-PRPs were putatively ascribed to II-2 and IB-1 nonphosphorylated, II-2 and IB-1 missing the C-terminal arginine residue, and the 1-62 fragment of IB-6, named P-J peptide. A correlation matrix analysis revealed a cluster of correlation among all the basic PRPs (apart from the P-B peptide) which is in agreement with their common parotid origin.Entities:
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Year: 2004 PMID： 15359733 DOI： 10.1021/pr049953c
Source DB: PubMed Journal: J Proteome Res ISSN： 1535-3893 Impact factor: 4.466