| Literature DB >> 15359726 |
Rupa S Rao1, Steven R Visuri, Mary T McBride, Joanna S Albala, Dennis L Matthews, Matthew A Coleman.
Abstract
Immobilized antibody microarrays were compared to the Luminex flow cytometry system that utilizes suspensions of polystyrene microbeads covalently coupled with capture antibodies. The two immunoassays were performed for comparison of reproducibility, limits of detection and dynamic range. The Luminex system showed lower limits of detection and increased dynamic range among samples whereas the protein microarrays could be more amenable to miniaturization. Both technologies were capable of sensitive multiplexed detection.Entities:
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Year: 2004 PMID: 15359726 DOI: 10.1021/pr034130t
Source DB: PubMed Journal: J Proteome Res ISSN: 1535-3893 Impact factor: 4.466