Literature DB >> 15359389

Results of a mechanical Duhamel pull-through for the treatment of Hirschsprung's disease and intestinal neuronal dysplasia.

Girolamo Mattioli1, Marco Castagnetti, Giuseppe Martucciello, Vincenzo Jasonni.   

Abstract

BACKGROUND/
PURPOSE: The authors analyzed the results of a modified entirely mechanical Duhamel pull-through for the treatment of Hirschsprung' disease or type B intestinal neuronal dysplasia. The aim of the follow-up was to evaluate results of a Duhamel procedure entirely performed with the use of staplers.
METHODS: Fifty-six patients were followed up to detect complications and outcome. Patients were evaluated clinically, and, when symptoms were present, a suction biopsy with histochemical analysis, an x-ray contrast enema, or an endoscopy was performed.
RESULTS: Early complications developed in 4 cases (7%) including a case of leakage (1.8%). No patient experienced recurrence. During a mean follow-up of 49 months, further complications occurred in 16 other patients: 4 adhesive obstructions requiring surgery, 3 strictures, 5 chronic bleeding, 4 fecaloma formation, 2 urinary problems, and 13 postoperative enterocolitis. Four patients (7%) had more than 3 passages of liquid stools per day, and 3 of them who had an ileal pull-through had constant soiling. Thirty-seven children (68.5%) had 1 to 2 bowel movements per day and were continent. Seven (13%) had less than 3 bowel movements per week. Three children who underwent total colectomy were incontinent (5.5%). Three more children (5.5%) have not yet reached the age for continence. Forty-nine parents (87%) judged the outcome satisfactory.
CONCLUSIONS: Follow-up of mechanical Duhamel pull-through showed an acceptable long-term outcome. An increased risk of incontinence is present in case of ileal pull-through, whereas constipation is more frequent after partial colon resection, regardless of the type of intestinal neuronal malformation.

Entities:  

Mesh:

Year:  2004        PMID: 15359389     DOI: 10.1016/j.jpedsurg.2004.05.007

Source DB:  PubMed          Journal:  J Pediatr Surg        ISSN: 0022-3468            Impact factor:   2.545


  5 in total

Review 1.  Intestinal neuronal dysplasia type B: A still little known diagnosis for organic causes of intestinal chronic constipation.

Authors:  Pedro Luiz Toledo de Arruda Lourenção; Simone Antunes Terra; Erika Veruska Paiva Ortolan; Maria Aparecida Marchesan Rodrigues
Journal:  World J Gastrointest Pharmacol Ther       Date:  2016-08-06

2.  Laparoscopic extensive colectomy with transanal Soave pull-through for intestinal neuronal dysplasia in 17 children.

Authors:  Shao-Tao Tang; Ying Yang; Guo-Bin Wang; Qiang-Song Tong; Yong-Zhong Mao; Yong Wang; Shi-Wang Li; Qing-Lan Ruan
Journal:  World J Pediatr       Date:  2010-02-09       Impact factor: 2.764

3.  Distal Loop Colonoscopy-Assisted Transanal Excision of Retained Spur after Duhamel's Procedure.

Authors:  K Senthamizhselvan; Pazhanivel Mohan; Bikash Kumar Naredi; Barath Jagadisan
Journal:  J Indian Assoc Pediatr Surg       Date:  2020-06-24

4.  Long-term follow-up of patients with intestinal neuronal dysplasia type B: Protocol for an observational, ambispective, and comparative study.

Authors:  Pedro Luiz Toledo de Arruda Lourenção; Erika Veruska Paiva Ortolan; Laura Luiza Minelli Rosa; Marcos Curcio Angelini; Simone Antunes Terra; Maria Aparecida Marchesan Rodrigues
Journal:  Medicine (Baltimore)       Date:  2017-07       Impact factor: 1.889

5.  Intestinal neuronal dysplasia type B in adults: a controversial entity.

Authors:  Vasillis Vougas; Konstantinos Vardas; Christos Christou; Georgios Papadimitriou; Evangelia Florou; Christina Magkou; Dimitrios Karamanolis; Dimitrios Manganas; Spiros Drakopoulos
Journal:  Case Rep Gastroenterol       Date:  2014-01-09
  5 in total

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