| Literature DB >> 15358530 |
Riccardo Sgarra1, Alessandra Rustighi, Michela A Tessari, Julie Di Bernardo, Sandro Altamura, Alfredo Fusco, Guidalberto Manfioletti, Vincenzo Giancotti.
Abstract
The structural characteristics of the three nuclear phosphoproteins of the high mobility group A family are outlined and related to their participation in chromatin structure alteration in many biological processes such as gene expression, neoplastic transformation, differentiation, and apoptosis. The elevated expression of these proteins in tumor cells and their post-translational modifications, such as phosphorylation, acetylation and methylation, are discussed and suggested as suitable targets for cancer chemotherapy.Entities:
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Year: 2004 PMID： 15358530 DOI： 10.1016/j.febslet.2004.08.013
Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124