| Literature DB >> 15358283 |
Braj Bhushan Lohray1, Vidya Bhushan Lohray, Brijesh Kumar Srivastava, Prashant B Kapadnis, Purvi Pandya.
Abstract
Synthesis of a number of 4,5,6,7-tetrahydro-thieno[3,2-c]pyridine substituted oxazolidinones have been reported. They have been screened against a panel of Gram-positive pathogens including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalis. A SAR has been developed. Compound 15 showed comparable activity (MIC) to linezolid and superior to eperezolid.Entities:
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Year: 2004 PMID： 15358283 DOI： 10.1016/j.bmc.2004.07.019
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641