Literature DB >> 1535722

Selective inhibition of cough and bronchoconstriction in conscious guinea pigs.

K Forsberg1, J A Karlsson, C Zackrisson, C G Persson.   

Abstract

In guinea-pigs citric acid-induced cough and bronchoconstriction were inhibited by beta 2-agonist and xanthine drugs. Lidocaine inhibited only cough. Cromoglycate and ipratropium bromide inhibited only bronchoconstriction. We conclude that cough and bronchoconstriction in guinea-pigs are distinct reflexes and that the inhibitory pharmacology of these airway reflexes may agree in many respects, with that observed in asthmatic subjects.

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Year:  1992        PMID: 1535722     DOI: 10.1159/000196030

Source DB:  PubMed          Journal:  Respiration        ISSN: 0025-7931            Impact factor:   3.580


  4 in total

1.  The use of the nose to study the inflammatory response of the respiratory tract.

Authors:  C G Persson; C Svensson; L Greiff; M Anderson; P Wollmer; U Alkner; I Erjefält
Journal:  Thorax       Date:  1992-12       Impact factor: 9.139

2.  TRPV1 antagonists attenuate antigen-provoked cough in ovalbumin sensitized guinea pigs.

Authors:  Robbie L McLeod; Xiomara Fernandez; Craig C Correll; Tara P Phelps; Yanlin Jia; Xin Wang; John A Hey
Journal:  Cough       Date:  2006-12-15

3.  Antitussive, anti-pyretic and toxicological evaluation of Ma-Xing-Gan-Shi-Tang in rodents.

Authors:  Yu-Chin Lin; Ching-Wen Chang; Chi-Rei Wu
Journal:  BMC Complement Altern Med       Date:  2016-11-10       Impact factor: 3.659

Review 4.  The Prospect for Potent Sodium Voltage-Gated Channel Blockers to Relieve an Excessive Cough.

Authors:  M Brozmanova; N Pavelkova
Journal:  Physiol Res       Date:  2020-03-27       Impact factor: 1.881

  4 in total

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