Literature DB >> 15355757

Recent understanding in the mechanisms of addiction.

Peter W Kalivas1.   

Abstract

The rewarding effects of drugs of abuse have been linked to increases in dopamine transmission. However, changes in brain chemistry and morphology that are produced in addiction underlie the long-lasting vulnerability to relapse and are more closely linked with the adaptations in excitatory transmission. The drug-induced changes in excitatory transmission seem to be pathologic exacerbations of normal forms of brain plasticity, and they occur in the brain areas linked by neuroimaging studies in addicted patients to craving and relapse. This review describes the brain adaptations produced in excitatory transmission by addictive drugs and identifies new potential sites of pharmacotherapeutic intervention to ameliorate addiction.

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Year:  2004        PMID： 15355757     DOI： 10.1007/s11920-004-0021-0

Source DB:  PubMed          Journal:  Curr Psychiatry Rep        ISSN： 1523-3812            Impact factor:   5.285


  40 in total

Review 1.  Drug addiction, dysregulation of reward, and allostasis.

Authors:  G F Koob; M Le Moal
Journal:  Neuropsychopharmacology       Date:  2001-02       Impact factor: 7.853

Review 2.  Molecular basis of long-term plasticity underlying addiction.

Authors:  E J Nestler
Journal:  Nat Rev Neurosci       Date:  2001-02       Impact factor: 34.870

3.  Repeated cocaine administration alters the electrophysiological properties of prefrontal cortical neurons.

Authors:  H Trantham; K K Szumlinski; K McFarland; P W Kalivas; A Lavin
Journal:  Neuroscience       Date:  2002       Impact factor: 3.590

Review 4.  Accessory proteins for G protein-signaling systems: activators of G protein signaling and other nonreceptor proteins influencing the activation state of G proteins.

Authors:  Joe B Blumer; Stephen M Lanier
Journal:  Receptors Channels       Date:  2003

5.  Neuroadaptations in cystine-glutamate exchange underlie cocaine relapse.

Authors:  David A Baker; Krista McFarland; Russell W Lake; Hui Shen; Xing-Chun Tang; Shigenobu Toda; Peter W Kalivas
Journal:  Nat Neurosci       Date:  2003-07       Impact factor: 24.884

Review 6.  The temporal sequence of changes in gene expression by drugs of abuse.

Authors:  Peter W Kalivas; Shigenobu Toda; M Scott Bowers; David A Baker; M Behnam Ghasemzadeh
Journal:  Methods Mol Med       Date:  2003

Review 7.  The nucleus accumbens: gateway for limbic structures to reach the motor system?

Authors:  H J Groenewegen; C I Wright; A V Beijer
Journal:  Prog Brain Res       Date:  1996       Impact factor: 2.453

8.  Regulation of gene expression and cocaine reward by CREB and DeltaFosB.

Authors:  Colleen A McClung; Eric J Nestler
Journal:  Nat Neurosci       Date:  2003-10-19       Impact factor: 24.884

Review 9.  Brain dopamine and reward.

Authors:  R A Wise; P P Rompre
Journal:  Annu Rev Psychol       Date:  1989       Impact factor: 24.137

10.  Identification of PSD-95 as a regulator of dopamine-mediated synaptic and behavioral plasticity.

Authors:  Wei-Dong Yao; Raul R Gainetdinov; Margaret I Arbuckle; Tatyana D Sotnikova; Michel Cyr; Jean-Martin Beaulieu; Gonzalo E Torres; Seth G N Grant; Marc G Caron
Journal:  Neuron       Date:  2004-02-19       Impact factor: 17.173
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  27 in total

Review 1.  Gene-environment interplay in alcoholism and other substance abuse disorders: expressions of heritability and factors influencing vulnerability.

Authors:  Tomas Palomo; R M Kostrzewa; R J Beninger; T Archer
Journal:  Neurotox Res       Date:  2004       Impact factor: 3.911

2.  Corticostriatal Afferents Modulate Responsiveness to Psychostimulant Drugs and Drug-Associated Stimuli.

Authors:  K A Kerstetter; A M Wunsch; K G Nakata; E Donckels; J F Neumaier; Susan M Ferguson
Journal:  Neuropsychopharmacology       Date:  2015-08-20       Impact factor: 7.853

Review 3.  Recent advances in the psychotherapy of addictive disorders.

Authors:  Kathleen M Carroll
Journal:  Curr Psychiatry Rep       Date:  2005-10       Impact factor: 5.285

Review 4.  Behavioral perspectives on the neuroscience of drug addiction.

Authors:  Gail Winger; James H Woods; Chad M Galuska; Tammy Wade-Galuska
Journal:  J Exp Anal Behav       Date:  2005-11       Impact factor: 2.468

Review 5.  Homers regulate drug-induced neuroplasticity: implications for addiction.

Authors:  Karen K Szumlinski; Alexis W Ary; Kevin D Lominac
Journal:  Biochem Pharmacol       Date:  2007-07-27       Impact factor: 5.858

6.  Histone deacetylase 5 limits cocaine reward through cAMP-induced nuclear import.

Authors:  Makoto Taniguchi; Maria B Carreira; Laura N Smith; Benjamin C Zirlin; Rachael L Neve; Christopher W Cowan
Journal:  Neuron       Date:  2012-01-12       Impact factor: 17.173

7.  Increased Sensitivity to Cocaine Self-Administration in HIV-1 Transgenic Rats is Associated with Changes in Striatal Dopamine Transporter Binding.

Authors:  Scot McIntosh; Tammy Sexton; Lindsey P Pattison; Steven R Childers; Scott E Hemby
Journal:  J Neuroimmune Pharmacol       Date:  2015-03-10       Impact factor: 4.147

8.  Repeated ketamine exposure induces an enduring resilient phenotype in adolescent and adult rats.

Authors:  Eric M Parise; Lyonna F Alcantara; Brandon L Warren; Katherine N Wright; Roey Hadad; Omar K Sial; Kyle G Kroeck; Sergio D Iñiguez; Carlos A Bolaños-Guzmán
Journal:  Biol Psychiatry       Date:  2013-06-19       Impact factor: 13.382

9.  A sensitizing D-amphetamine dose regimen induces long-lasting spinophilin and VGLUT1 protein upregulation in the rat diencephalon.

Authors:  Steven R Boikess; Steven J O'Dell; John F Marshall
Journal:  Neurosci Lett       Date:  2009-11-20       Impact factor: 3.046

10.  Intra-accumbal Tat1-72 alters acute and sensitized responses to cocaine.

Authors:  S B Harrod; C F Mactutus; S Fitting; U Hasselrot; R M Booze
Journal:  Pharmacol Biochem Behav       Date:  2008-10       Impact factor: 3.533
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