| Literature DB >> 15355039 |
Mark E Scott1, Wooseok Han, Mark Lautens.
Abstract
[reaction: see text] A highly diastereoselective MgI(2)-mediated ring expansion of methylenecyclopropane amides to functionalized pyrrolidines has been developed using chiral aromatic sulfinimines. The 2,3,4-trisubstituted pyrrolidines were isolated in generally good to excellent yields and in excellent diastereoselectivities for aromatic and heterocyclic sulfinimines.Entities:
Year: 2004 PMID： 15355039 DOI： 10.1021/ol048769u
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005