Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 The role of coordination chemistry in the development of target-specific radiopharmaceuticals.

Literature DB >> 15354226

The role of coordination chemistry in the development of target-specific radiopharmaceuticals.

Abstract

There is a great current interest in developing target-specific radiopharmaceuticals for early detection of diseases and radiotherapy of cancers. This critical review will focus on the role of coordination chemistry in the development of target-specific radiopharmaceuticals. It will also discuss the recent development in technetium, copper, gallium, indium, yttrium and lanthanide chemistry, as well as analytical tools for quality control and characterization of radiolabeled small biomolecules (159 references).

Entities: Chemical Disease

Mesh：

Substances：

Year: 2004 PMID： 15354226 DOI： 10.1039/b309961j

Source DB: PubMed Journal: Chem Soc Rev ISSN： 0306-0012 Impact factor: 54.564

Keyword Cloud
Cited

48 in total

1. (99m)Tc-bioorthogonal click chemistry reagent for in vivo pretargeted imaging.

Authors: María Fernanda García; Xiuli Zhang; Manankumar Shah; Jessica Newton-Northup; Pablo Cabral; Hugo Cerecetto; Thomas Quinn
Journal: Bioorg Med Chem Date: 2016-01-29 Impact factor: 3.641

Review 2. Bifunctional coupling agents for radiolabeling of biomolecules and target-specific delivery of metallic radionuclides.

Authors: Shuang Liu
Journal: Adv Drug Deliv Rev Date: 2008-04-23 Impact factor: 15.470

3. Synthesis and opioid receptor binding of indium (III) and [¹¹¹In]-labeled macrocyclic conjugates of diprenorphine: novel ligands designed for imaging studies of peripheral opioid receptors.

Authors: Shefali Srivastava; Emily A Fergason-Cantrell; Roger I Nahas; John R Lever
Journal: Tetrahedron Date: 2016-08-04 Impact factor: 2.457

Review 4. Application of metal coordination chemistry to explore and manipulate cell biology.

Authors: Kathryn L Haas; Katherine J Franz
Journal: Chem Rev Date: 2009-10 Impact factor: 60.622

5. Complexes possessing rare "tertiary" sulfonamide nitrogen-to-metal bonds of normal length: fac-[Re(CO)3(N(SO2R)dien)]PF6 complexes with hydrophilic sulfonamide ligands.

Authors: Pramuditha L Abhayawardhana; Patricia A Marzilli; Frank R Fronczek; Luigi G Marzilli
Journal: Inorg Chem Date: 2014-01-08 Impact factor: 5.165

9. Formation of a metal-to-nitrogen bond of normal length by a neutral sufonamide group within a tridentate ligand. A new approach to radiopharmaceutical bioconjugation.

Authors: Theshini Perera; Pramuditha Abhayawardhana; Patricia A Marzilli; Frank R Fronczek; Luigi G Marzilli
Journal: Inorg Chem Date: 2013-02-19 Impact factor: 5.165

Review 10. Radiolabeled cyclic RGD peptides as integrin alpha(v)beta(3)-targeted radiotracers: maximizing binding affinity via bivalency.

Authors: Shuang Liu
Journal: Bioconjug Chem Date: 2009-12 Impact factor: 4.774

The role of coordination chemistry in the development of target-specific radiopharmaceuticals.

1. (99m)Tc-bioorthogonal click chemistry reagent for in vivo pretargeted imaging.

Review 2. Bifunctional coupling agents for radiolabeling of biomolecules and target-specific delivery of metallic radionuclides.

3. Synthesis and opioid receptor binding of indium (III) and [¹¹¹In]-labeled macrocyclic conjugates of diprenorphine: novel ligands designed for imaging studies of peripheral opioid receptors.

Review 4. Application of metal coordination chemistry to explore and manipulate cell biology.

5. Complexes possessing rare "tertiary" sulfonamide nitrogen-to-metal bonds of normal length: fac-[Re(CO)3(N(SO2R)dien)]PF6 complexes with hydrophilic sulfonamide ligands.

6. Metallic radionuclides in the development of diagnostic and therapeutic radiopharmaceuticals.

7. Effect of Peptide-Chelate Architecture on Metabolic Stability of Peptide-based MRI Contrast Agents.

Review 8. Tactics for preclinical validation of receptor-binding radiotracers.

9. Formation of a metal-to-nitrogen bond of normal length by a neutral sufonamide group within a tridentate ligand. A new approach to radiopharmaceutical bioconjugation.

Review 10. Radiolabeled cyclic RGD peptides as integrin alpha(v)beta(3)-targeted radiotracers: maximizing binding affinity via bivalency.

The role of coordination chemistry in the development of target-specific radiopharmaceuticals.

1. (99m)Tc-bioorthogonal click chemistry reagent for in vivo pretargeted imaging.

Review 2. Bifunctional coupling agents for radiolabeling of biomolecules and target-specific delivery of metallic radionuclides.

3. Synthesis and opioid receptor binding of indium (III) and [111In]-labeled macrocyclic conjugates of diprenorphine: novel ligands designed for imaging studies of peripheral opioid receptors.

Review 4. Application of metal coordination chemistry to explore and manipulate cell biology.

5. Complexes possessing rare "tertiary" sulfonamide nitrogen-to-metal bonds of normal length: fac-[Re(CO)3(N(SO2R)dien)]PF6 complexes with hydrophilic sulfonamide ligands.

6. Metallic radionuclides in the development of diagnostic and therapeutic radiopharmaceuticals.

7. Effect of Peptide-Chelate Architecture on Metabolic Stability of Peptide-based MRI Contrast Agents.

Review 8. Tactics for preclinical validation of receptor-binding radiotracers.

9. Formation of a metal-to-nitrogen bond of normal length by a neutral sufonamide group within a tridentate ligand. A new approach to radiopharmaceutical bioconjugation.

Review 10. Radiolabeled cyclic RGD peptides as integrin alpha(v)beta(3)-targeted radiotracers: maximizing binding affinity via bivalency.

3. Synthesis and opioid receptor binding of indium (III) and [¹¹¹In]-labeled macrocyclic conjugates of diprenorphine: novel ligands designed for imaging studies of peripheral opioid receptors.