Literature DB >> 15353920

Postoperative pulmonary embolism in a young female accompanying with Factor V Leiden mutation and hereditary sypherocytosis.

Demet Karnak1, Sumru Beder, Oya Kayacan, Ozlem Berk.   

Abstract

A 20 year-old female, heterozygous for Factor V Leiden mutation (FVLM) is presented. Her personal history was prominent for severe anaemia during her gestation. Aetiology of anaemia was found to be hereditary spherocytosis (HS). Intrauterine foetal death had occurred at 20 weeks of gestational age. Two days after curettage, she developed pulmonary embolism (PE). This is an unusual case of pulmonary embolism and intrauterine foetal death coexisting with FVLM and/or HS. We present the case so that a general practitioner or haematologist can hardly see such cases in daily practice. Hence, a young female with PE should be screened for hypercoagulable states including FVLM or HS.

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Year:  2004        PMID: 15353920     DOI: 10.1023/B:THRO.0000040491.79092.11

Source DB:  PubMed          Journal:  J Thromb Thrombolysis        ISSN: 0929-5305            Impact factor:   2.300


  22 in total

1.  Comparison of the risk of pulmonary embolism and deep vein thrombosis in the presence of factor V Leiden or prothrombin G20210A.

Authors:  A J Ordóñez; J M Carreira; C R Alvarez; J M Rodríguez; M V Alvarez; E Coto
Journal:  Thromb Haemost       Date:  2000-02       Impact factor: 5.249

2.  Factor V Leiden paradox: risk of deep-vein thrombosis but not of pulmonary embolism.

Authors:  H Bounameaux
Journal:  Lancet       Date:  2000-07-15       Impact factor: 79.321

3.  Relative risk of pulmonary embolism and deep vein thrombosis in association with the factor V Leiden mutation in a United Kingdom population.

Authors:  T P Baglin; K Brown; D Williamson; P Baker; R Luddington
Journal:  Thromb Haemost       Date:  1997-06       Impact factor: 5.249

4.  Fatal pulmonary embolism during legal induced abortion in the United States from 1972 to 1985.

Authors:  H W Lawson; H K Atrash; A L Franks
Journal:  Am J Obstet Gynecol       Date:  1990-04       Impact factor: 8.661

5.  Increased risk for fetal loss in carriers of the factor V Leiden mutation.

Authors:  J R Meinardi; S Middeldorp; P J de Kam; M M Koopman; E C van Pampus; K Hamulyák; M H Prins; H R Büller; J van der Meer
Journal:  Ann Intern Med       Date:  1999-05-04       Impact factor: 25.391

6.  The factor V Leiden mutation may predispose women to severe preeclampsia.

Authors:  D S Dizon-Townson; L M Nelson; K Easton; K Ward
Journal:  Am J Obstet Gynecol       Date:  1996-10       Impact factor: 8.661

7.  Low prevalence of factor V:Q506 in 41 patients with isolated pulmonary embolism.

Authors:  I Martinelli; M Cattaneo; D Panzeri; P M Mannucci
Journal:  Thromb Haemost       Date:  1997-03       Impact factor: 5.249

8.  Is the prevalence of the factor V Leiden mutation in patients with pulmonary embolism and deep vein thrombosis really different?

Authors:  F Turkstra; R Karemaker; P M Kuijer; M H Prins; H R Büller
Journal:  Thromb Haemost       Date:  1999-03       Impact factor: 5.249

9.  Coagulation factor V gene mutation increases the risk of venous thrombosis in behçet's disease.

Authors:  A Gül; U Ozbek; C Oztürk; M Inanç; M Koniçe; T Ozçelik
Journal:  Br J Rheumatol       Date:  1996-11

10.  Mutation in blood coagulation factor V associated with resistance to activated protein C.

Authors:  R M Bertina; B P Koeleman; T Koster; F R Rosendaal; R J Dirven; H de Ronde; P A van der Velden; P H Reitsma
Journal:  Nature       Date:  1994-05-05       Impact factor: 49.962

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