AIM: To evaluate right ventricular wall motion abnormalities in healthy subjects using a new segmental model for the right ventricle. METHODS AND RESULTS: 29 healthy subjects (9 female, 20 male, mean age 48.9+/-15 years) underwent cardiovascular magnetic resonance imaging (CMR; 1.5-Tesla Sonata, Siemens, Erlangen, Germany) for the evaluation of cardiac function and right ventricular wall motion. A steady-state free precession gradient-echo sequence (TrueFISP) was used. Right ventricular wall motion was analyzed, and the site of areas of disordered motion was classified according to the new segmental model. Such areas were seen in 27 (93.1%) of the 29 subjects. Dyskinesia was found in 22 subjects (75.9%), hypokinesia in 11 (37.9%), and bulging in 8 (27.6%). The number of wall motion abnormalities diagnosed was significantly higher in the transverse plane (86.2%) than in the short-axis plane (13.8%) and the horizontal longitudinal plane (41.4%; p = 0.000). CONCLUSION: Right ventricular wall motion abnormalities are one of the criteria for the diagnosis of arrhythmogenic right ventricular cardiomyopathy. However, our findings indicate that they may also be seen around the insertion of the moderator band in healthy subjects, so that the significance of their presence at this site in patients undergoing diagnostic investigations for this disease should be interpreted with caution.
AIM: To evaluate right ventricular wall motion abnormalities in healthy subjects using a new segmental model for the right ventricle. METHODS AND RESULTS: 29 healthy subjects (9 female, 20 male, mean age 48.9+/-15 years) underwent cardiovascular magnetic resonance imaging (CMR; 1.5-Tesla Sonata, Siemens, Erlangen, Germany) for the evaluation of cardiac function and right ventricular wall motion. A steady-state free precession gradient-echo sequence (TrueFISP) was used. Right ventricular wall motion was analyzed, and the site of areas of disordered motion was classified according to the new segmental model. Such areas were seen in 27 (93.1%) of the 29 subjects. Dyskinesia was found in 22 subjects (75.9%), hypokinesia in 11 (37.9%), and bulging in 8 (27.6%). The number of wall motion abnormalities diagnosed was significantly higher in the transverse plane (86.2%) than in the short-axis plane (13.8%) and the horizontal longitudinal plane (41.4%; p = 0.000). CONCLUSION: Right ventricular wall motion abnormalities are one of the criteria for the diagnosis of arrhythmogenic right ventricular cardiomyopathy. However, our findings indicate that they may also be seen around the insertion of the moderator band in healthy subjects, so that the significance of their presence at this site in patients undergoing diagnostic investigations for this disease should be interpreted with caution.
Authors: Gianfranco Buja; N A Mark Estes; Thomas Wichter; Domenico Corrado; Frank Marcus; Gaetano Thiene Journal: Prog Cardiovasc Dis Date: 2008 Jan-Feb Impact factor: 8.194
Authors: Frank I Marcus; Wojciech Zareba; Hugh Calkins; Jeffrey A Towbin; Cristina Basso; David A Bluemke; N A Mark Estes; Michael H Picard; Danita Sanborn; Gaetano Thiene; Thomas Wichter; David Cannom; David J Wilber; Melvin Scheinman; Henry Duff; James Daubert; Mario Talajic; Andrew Krahn; Michael Sweeney; Hasan Garan; Scott Sakaguchi; Bruce B Lerman; Charles Kerr; Jack Kron; Jonathan S Steinberg; Duane Sherrill; Kathleen Gear; Mary Brown; Patricia Severski; Slava Polonsky; Scott McNitt Journal: Heart Rhythm Date: 2009-03-11 Impact factor: 6.343
Authors: Neda Rastegar; Jeremy R Burt; Celia P Corona-Villalobos; Anneline S Te Riele; Cynthia A James; Brittney Murray; Hugh Calkins; Harikrishna Tandri; David A Bluemke; Stefan L Zimmerman; Ihab R Kamel Journal: Radiographics Date: 2014-10 Impact factor: 5.333
Authors: M Perazzolo Marra; S Rizzo; B Bauce; M De Lazzari; K Pilichou; D Corrado; G Thiene; S Iliceto; C Basso Journal: Herz Date: 2015-06 Impact factor: 1.443