Literature DB >> 15346058

Intercalary femur and tibia segmental allografts provide an acceptable alternative in reconstructing tumor resections.

D Luis Muscolo1, Miguel A Ayerza, Luis Aponte-Tinao, Maximiliano Ranalletta, Eduardo Abalo.   

Abstract

Intercalary femur and tibia segmental allografts were implanted in 59 consecutive patients after segmental resection-52 for malignant and seven for benign aggressive bone tumors. The patients were followed up for an average of 5 years. Allograft survival was determined with the Kaplan-Meier method. Infection, fracture, and nonunion rates were determined. The overall 5-year survivorship for the 59 intercalary allografts was 79%, and we found no significant differences between allograft survival in patients receiving or not receiving adjuvant chemotherapy. Infection and fracture rates were 5% and 7% respectively. From 118 host-donor junctions, 11 did not initially heal (9%). The nonunion rate (10 of 69 osteotomies) for diaphyseal junctions was higher than the rate (one of 49 osteotomies) for metaphyseal junctions. Although some patients required reoperations because of allograft complications, it seems that the use of intercalary allograft clearly has a place in the reconstruction of a segmental defect created by the resection of a tumor in the diaphyseal and /or metaphyseal portion of the femur or tibia.

Entities:  

Mesh:

Year:  2004        PMID: 15346058     DOI: 10.1097/01.blo.0000141652.93178.10

Source DB:  PubMed          Journal:  Clin Orthop Relat Res        ISSN: 0009-921X            Impact factor:   4.176


  52 in total

1.  Microsurgical reconstruction with vascularized fibula and massive bone allograft for bone tumors.

Authors:  Costantino Errani; Massimo Ceruso; Davide Maria Donati; Marco Manfrini
Journal:  Eur J Orthop Surg Traumatol       Date:  2018-12-05

2.  Similar survival but better function for patients after limb salvage versus amputation for distal tibia osteosarcoma.

Authors:  Andreas F Mavrogenis; Caterina Novella Abati; Carlo Romagnoli; Pietro Ruggieri
Journal:  Clin Orthop Relat Res       Date:  2012-01-24       Impact factor: 4.176

Review 3.  Limb salvage in the skeletally immature patient.

Authors:  Valerae O Lewis
Journal:  Curr Oncol Rep       Date:  2005-07       Impact factor: 5.075

4.  Effects of a new allograft processing procedure on graft healing in a canine model: a preliminary study.

Authors:  Kathleen S Beebe; Joseph Benevenia; Benjamin E Tuy; C Alex DePaula; Robert D Harten; William F Enneking
Journal:  Clin Orthop Relat Res       Date:  2008-08-19       Impact factor: 4.176

5.  Can bone scintigraphy predict the final outcome of pasteurized autografts?

Authors:  Ahmed Shawky Eid; Dae-Geun Jeon; Wan Hyeong Cho
Journal:  Skeletal Radiol       Date:  2010-02-23       Impact factor: 2.199

Review 6.  Intercalary reconstructions after bone tumor resections: a review of treatments.

Authors:  Georgios N Panagopoulos; Andreas F Mavrogenis; Cyril Mauffrey; Jan Lesenský; Andrea Angelini; Panayiotis D Megaloikonomos; Vasilios G Igoumenou; John Papanastassiou; Olga Savvidou; Pietro Ruggieri; Panayiotis J Papagelopoulos
Journal:  Eur J Orthop Surg Traumatol       Date:  2017-06-05

7.  Vascularized fibular medialization for reconstruction of the tibial defects following tumour excision.

Authors:  Abed El-Negery; Nabil Ahmed Elmoghazy; Mohamed Serry Abd-Ellatif; Adham Elgeidi
Journal:  Int Orthop       Date:  2017-04-19       Impact factor: 3.075

8.  Outcomes of a Modular Intercalary Endoprosthesis as Treatment for Segmental Defects of the Femur, Tibia, and Humerus.

Authors:  Joseph Benevenia; Rainer Kirchner; Francis Patterson; Kathleen Beebe; Dieter C Wirtz; Steven Rivero; Mark Palma; Max J Friedrich
Journal:  Clin Orthop Relat Res       Date:  2016-02       Impact factor: 4.176

9.  Survival of massive allografts in segmental oncological bone defect reconstructions.

Authors:  P H J Bullens; N M Minderhoud; M C de Waal Malefijt; R P H Veth; P Buma; H W B Schreuder
Journal:  Int Orthop       Date:  2008-12-03       Impact factor: 3.075

10.  Osteogenic protein-1 for long bone nonunion: an evidence-based analysis.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2005-04-01
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.