Literature DB >> 15345143

Solar ultraviolet A radiation: an oxidizing skin carcinogen that activates heme oxygenase-1.

R M Tyrrell1.   

Abstract

Ultraviolet A (UVA: 320-380 nm) radiation is an oxidizing carcinogen that has proved an ideal agent for demonstrating the oxidant inducibility of the mammalian heme oxygenase-1 (HO-1) gene. The UVA response in cultured human skin fibroblasts and other cell types is mediated by singlet oxygen and is strongly influenced by cellular reducing equivalents. Free heme, an entity that can be generated by UVA irradiation of cells, also appears to be a critical intermediate that can directly influence both the transcriptional activation and repression of the HO-1 gene. Heme release is likely to be of central importance to the inflammatory response in skin and its abrogation by HO.

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Year:  2004        PMID： 15345143     DOI： 10.1089/ars.2004.6.835

Source DB:  PubMed          Journal:  Antioxid Redox Signal        ISSN： 1523-0864            Impact factor:   8.401


  20 in total

1.  The malondialdehyde-derived fluorophore DHP-lysine is a potent sensitizer of UVA-induced photooxidative stress in human skin cells.

Authors:  Sarah D Lamore; Sara Azimian; David Horn; Bobbi L Anglin; Koji Uchida; Christopher M Cabello; Georg T Wondrak
Journal:  J Photochem Photobiol B       Date:  2010-07-30       Impact factor: 6.252

Review 2.  The unfolded protein response triggered by environmental factors.

Authors:  Masanori Kitamura
Journal:  Semin Immunopathol       Date:  2013-04-04       Impact factor: 9.623

3.  Thioredoxin reductase activity may be more important than GSH level in protecting human lens epithelial cells against UVA light.

Authors:  Vanita A Padgaonkar; Victor R Leverenz; Aparna V Bhat; Sara E Pelliccia; Frank J Giblin
Journal:  Photochem Photobiol       Date:  2015-01-08       Impact factor: 3.421

4.  The proteasome is an integral part of solar ultraviolet a radiation-induced gene expression.

Authors:  Betul Catalgol; Isabella Ziaja; Nicolle Breusing; Tobias Jung; Annika Höhn; Buket Alpertunga; Peter Schroeder; Niki Chondrogianni; Efstathios S Gonos; Isabelle Petropoulos; Bertrand Friguet; Lars-Oliver Klotz; Jean Krutmann; Tilman Grune
Journal:  J Biol Chem       Date:  2009-08-18       Impact factor: 5.157

5.  Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress.

Authors:  Georg T Wondrak; Christopher M Cabello; Nicole F Villeneuve; Shirley Zhang; Stephanie Ley; Yanjie Li; Zheng Sun; Donna D Zhang
Journal:  Free Radic Biol Med       Date:  2008-04-26       Impact factor: 7.376

Review 6.  Topical Vitamin C and the Skin: Mechanisms of Action and Clinical Applications.

Authors:  Firas Al-Niaimi; Nicole Yi Zhen Chiang
Journal:  J Clin Aesthet Dermatol       Date:  2017-07-01

7.  NF-E2-related factor 2 regulates the stress response to UVA-1-oxidized phospholipids in skin cells.

Authors:  Florian Gruber; Herbert Mayer; Barbara Lengauer; Veronika Mlitz; John M Sanders; Alexandra Kadl; Martin Bilban; Rainer de Martin; Oswald Wagner; Thomas W Kensler; Masayuki Yamamoto; Norbert Leitinger; Erwin Tschachler
Journal:  FASEB J       Date:  2009-08-31       Impact factor: 5.191

Review 8.  Ultraviolet Radiation in Wound Care: Sterilization and Stimulation.

Authors:  Asheesh Gupta; Pinar Avci; Tianhong Dai; Ying-Ying Huang; Michael R Hamblin
Journal:  Adv Wound Care (New Rochelle)       Date:  2013-10       Impact factor: 4.730

Review 9.  Targeting the redox balance in inflammatory skin conditions.

Authors:  Frank A D T G Wagener; Carine E Carels; Ditte M S Lundvig
Journal:  Int J Mol Sci       Date:  2013-04-26       Impact factor: 5.923

10.  Different oxidative stress response in keratinocytes and fibroblasts of reconstructed skin exposed to non extreme daily-ultraviolet radiation.

Authors:  Claire Marionnet; Cécile Pierrard; François Lejeune; Juliette Sok; Marie Thomas; Françoise Bernerd
Journal:  PLoS One       Date:  2010-08-10       Impact factor: 3.240
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