Literature DB >> 15343455

[Traumatic optic neuropathy--the present state].

H Wilhelm1.   

Abstract

Direct or indirect trauma may damage the optic nerve and result in permanent visual loss. The diagnosis of traumatic optic neuropathy is not always straightforward and is complicated by unfavourable circumstances for the examination. The diagnosis should only by established if it can be based on a clear objective finding, a relative afferent pupillary defect or a pathological flash-evoked visual response. Concerning therapy, surgical decompression (even without direct injury to the nerve) or megadose steroids or both in combination have been recommended. But even spontaneous improvement may occur. A large multicentre study could not demonstrate a significant advantage for any of the measures recommended, not even against the spontaneous course. However, the study was not randomised. In animal experiments steroids have shown an unfavourable effect. Currently, therapeutic decisions have to be made on an individual basis, in the absence of any evidence-based recommendations.

Entities:  

Mesh:

Substances:

Year:  2004        PMID: 15343455     DOI: 10.1055/s-2004-813268

Source DB:  PubMed          Journal:  Klin Monbl Augenheilkd        ISSN: 0023-2165            Impact factor:   0.700


  3 in total

1.  [Posttraumatic amaurosis after complex frontobasal fracture. Differential diagnosis and therapy].

Authors:  P U Lohnstein; J Schipper; A Berlis; N-C Gellrich; W Maier
Journal:  HNO       Date:  2007-11       Impact factor: 1.284

2.  [Hematoma of the eye: there's more to this than meets the eye!].

Authors:  I Loewe; H Sachs
Journal:  Ophthalmologe       Date:  2012-12       Impact factor: 1.059

3.  Protective effects of human umbilical cord blood stem cell intravitreal transplantation against optic nerve injury in rats.

Authors:  Tantai Zhao; Yunqin Li; Luosheng Tang; Yuehua Li; Fang Fan; Bing Jiang
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2011-03-01       Impact factor: 3.117

  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.