OBJECTIVE: To characterize clinical features, associated problems, and outcomes for children with complex motor stereotypies who do not have mental retardation or pervasive developmental disorders. STUDY DESIGN: We performed a record review for 40 children (63% male) aged 9 months to 17 years with complex motor stereotypies between 1993 and 2003. RESULTS: Age at onset was at or before 3 years in 90% of the sample. Symptoms occurred at least once daily in 90%. Excitement was identified as a trigger in 70%. Movements stopped when cued in 98%, and none had stereotypies during sleep. A total of 25% had comorbid attention deficit hyperactivity disorder (ADHD), and 20% had a learning disability. Family history of stereotypies was identified in 25%, tics in 33%, ADHD in 10%, and mood-anxiety disorder in 38%. Pharmacotherapy to target associated conditions was used in 40%, and behavioral therapy was used in 23%. A total of 53% identified symptoms for more than 5 years. Movements resolved in 5% of the children, improved in 33%, were unchanged in 50%, and worsened in 13%. CONCLUSIONS: The clinical course of complex motor stereotypies appears chronic. Better understanding of the clinical features of complex stereotypies in primary care settings is essential for early diagnosis and management.
OBJECTIVE: To characterize clinical features, associated problems, and outcomes for children with complex motor stereotypies who do not have mental retardation or pervasive developmental disorders. STUDY DESIGN: We performed a record review for 40 children (63% male) aged 9 months to 17 years with complex motor stereotypies between 1993 and 2003. RESULTS: Age at onset was at or before 3 years in 90% of the sample. Symptoms occurred at least once daily in 90%. Excitement was identified as a trigger in 70%. Movements stopped when cued in 98%, and none had stereotypies during sleep. A total of 25% had comorbid attention deficit hyperactivity disorder (ADHD), and 20% had a learning disability. Family history of stereotypies was identified in 25%, tics in 33%, ADHD in 10%, and mood-anxiety disorder in 38%. Pharmacotherapy to target associated conditions was used in 40%, and behavioral therapy was used in 23%. A total of 53% identified symptoms for more than 5 years. Movements resolved in 5% of the children, improved in 33%, were unchanged in 50%, and worsened in 13%. CONCLUSIONS: The clinical course of complex motor stereotypies appears chronic. Better understanding of the clinical features of complex stereotypies in primary care settings is essential for early diagnosis and management.
Authors: Terence D Sanger; Daofen Chen; Darcy L Fehlings; Mark Hallett; Anthony E Lang; Jonathan W Mink; Harvey S Singer; Katharine Alter; Hilla Ben-Pazi; Erin E Butler; Robert Chen; Abigail Collins; Sudarshan Dayanidhi; Hans Forssberg; Eileen Fowler; Donald L Gilbert; Sharon L Gorman; Mark E Gormley; H A Jinnah; Barbara Kornblau; Kristin J Krosschell; Rebecca K Lehman; Colum MacKinnon; C J Malanga; Ronit Mesterman; Margaret Barry Michaels; Toni S Pearson; Jessica Rose; Barry S Russman; Dagmar Sternad; Kathy J Swoboda; Francisco Valero-Cuevas Journal: Mov Disord Date: 2010-08-15 Impact factor: 10.338
Authors: Marisela E Dy; Jeff L Waugh; Nutan Sharma; Heather O'Leary; Kush Kapur; Alissa M D'Gama; Mustafa Sahin; David K Urion; Walter E Kaufmann Journal: Pediatr Neurol Date: 2017-06-02 Impact factor: 3.372
Authors: E Mark Mahone; Matthew Ryan; Lisa Ferenc; Christina Morris-Berry; Harvey S Singer Journal: Dev Med Child Neurol Date: 2014-05-10 Impact factor: 5.449