Literature DB >> 15342854

Intussusception in early childhood: a cohort study of 1.7 million children.

Thea Kølsen Fischer1, Kristine Bihrmann, Michael Perch, Anders Koch, Jan Wohlfahrt, Mølbak Kåre, Mads Melbye.   

Abstract

OBJECTIVE: To describe incidence and temporal trends of intussusceptions in Danish children during 1980 to 2001.
METHODS: A population-based cohort study was conducted of 1.67 million children who were younger than 5 years during 1980 to 2001 and were followed up for 6.66 million person-years. The Danish National Patient Registry was used to identify cases of intussusception in the cohort. Age-specific incidence rates were main outcome measure.
RESULTS: A total of 1814 cases of intussusception among children who were younger than 5 years were reported from 1980 to 2001. The incidence rate remained fairly constant during 1980 to 1990 but decreased by 55% (95% confidence interval: 43%-65%) from 1990 to 2001. The reduction was most pronounced among children aged 3 to 5 months.
CONCLUSIONS: The incidence of intussusception among Danish children declined significantly during the 1990s, particularly among infants 3 to 5 months of age.

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Year:  2004        PMID: 15342854     DOI: 10.1542/peds.2004-0390

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  35 in total

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