Literature DB >> 15342200

Expression of hemokinin 1 mRNA by murine dendritic cells.

Daniel A Nelson1, Ian Marriott, Kenneth L Bost.   

Abstract

Hemokinin 1 is encoded by preprotachykinin C (PPT-C) mRNA, and has been proposed as a regulator of B and T cell lymphopoiesis. Here we demonstrate the expression of mouse PPT-C mRNA by CD11b+ macrophages, CD11c+ dendritic cells and in the microglial cell line EOC 13.31. Expression was detected in freshly isolated CD11b+CD11c+ bone marrow cells, as well as in M-CSF expanded bone marrow-derived macrophages and GM-CSF expanded bone marrow-derived dendritic cells. There was preferential expression of PPT-C mRNA in dendritic cell subpopulations that were CD11b+, but not B220+ or GR-1+. These studies are the first to demonstrate PPT-C mRNA expression by cells of the myeloid lineage. Copyright 2004 Elsevier B.V.

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Year:  2004        PMID： 15342200     DOI： 10.1016/j.jneuroim.2004.06.005

Source DB:  PubMed          Journal:  J Neuroimmunol        ISSN： 0165-5728            Impact factor:   3.478


  13 in total

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Journal:  Ann N Y Acad Sci       Date:  2010-11-22       Impact factor: 5.691

2.  Increase in hemokinin-1 mRNA in the spinal cord during the early phase of a neuropathic pain state.

Authors:  T Matsumura; A Sakai; M Nagano; M Sawada; H Suzuki; M Umino; H Suzuki
Journal:  Br J Pharmacol       Date:  2008-07-28       Impact factor: 8.739

Review 3.  Tachykinins and their receptors: contributions to physiological control and the mechanisms of disease.

Authors:  Martin S Steinhoff; Bengt von Mentzer; Pierangelo Geppetti; Charalabos Pothoulakis; Nigel W Bunnett
Journal:  Physiol Rev       Date:  2014-01       Impact factor: 37.312

4.  Design of a heterosubtypic epitope-based peptide vaccine fused with hemokinin-1 against influenza viruses.

Authors:  Shahla Shahsavandi; Mohammad Majid Ebrahimi; Kaveh Sadeghi; Homayoon Mahravani
Journal:  Virol Sin       Date:  2015-04-15       Impact factor: 4.327

5.  3,4-Methylenedioxymethamphetamine (MDMA) alters acute gammaherpesvirus burden and limits interleukin 27 responses in a mouse model of viral infection.

Authors:  Daniel A Nelson; Sam J Singh; Amy B Young; Melanie D Tolbert; Kenneth L Bost
Journal:  Drug Alcohol Depend       Date:  2011-01-26       Impact factor: 4.492

6.  Ecstasy (3,4-methylenedioxymethamphetamine) limits murine gammaherpesvirus-68 induced monokine expression.

Authors:  Daniel A Nelson; Jamie L Nirmaier; Sam J Singh; Melanie D Tolbert; Kenneth L Bost
Journal:  Brain Behav Immun       Date:  2008-02-15       Impact factor: 7.217

7.  Expression of neuronal trace amine-associated receptor (Taar) mRNAs in leukocytes.

Authors:  Daniel A Nelson; Melanie D Tolbert; Sam J Singh; Kenneth L Bost
Journal:  J Neuroimmunol       Date:  2007-09-27       Impact factor: 3.478

8.  Exacerbated metastatic disease in a mouse mammary tumor model following latent gammaherpesvirus infection.

Authors:  Vinita S Chauhan; Daniel A Nelson; Lopamudra Das Roy; Pinku Mukherjee; Kenneth L Bost
Journal:  Infect Agent Cancer       Date:  2012-05-29       Impact factor: 2.965

9.  Hemokinin-1 gene expression is upregulated in microglia activated by lipopolysaccharide through NF-κB and p38 MAPK signaling pathways.

Authors:  Atsushi Sakai; Kumiko Takasu; Makoto Sawada; Hidenori Suzuki
Journal:  PLoS One       Date:  2012-02-27       Impact factor: 3.240

10.  An expanded myeloid derived suppressor cell population does not play a role in gammaherpesvirus-exacerbated breast cancer metastases.

Authors:  Daniel A Nelson; Vinita S Chauhan; Melanie D Tolbert; Kenneth L Bost
Journal:  Infect Agent Cancer       Date:  2012-09-04       Impact factor: 2.965
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