Literature DB >> 1534104

Lumbar disk disease: epidemiology.

J W Frymoyer.   

Abstract

Sciatica is a common symptom that affects as many as 40% of the adult population at some time. However, clinically significant sciatica is much less common and occurs in only 4% to 6% of the population. Exactly how often the symptom is caused by lumbar disk herniation is uncertain; it is known that herniation can occur independent of symptoms. Among the factors associated with its occurrence are age, gender, occupation, cigarette smoking, and exposure to vehicular vibration. The contribution of other factors such as height, weight, and genetics is less certain. The majority of patients with sciatica appear to recover. Approximately 20% of patients with sciatica caused by lumbar herniation have a strong indication for surgical intervention. In the remainder, indications are based primarily on pain rather than functionally significant neurologic deficits. Because pain is the principle indication, there are wide variations in the rates of surgical intervention between countries, and, even within countries, there are significant regional variations. These variations appear to be driven less by specific medical factors and more by gender, occupation, income, education, and the surgeon's preference. Although the contribution of sciatica to low back pain disability remains uncertain, disability caused by low back pain and sciatica appears to be increasing at a rate disproportionate to population growth. To what degree surgery now contributes to that disability is uncertain, but limited information suggests that it may be substantial.

Entities:  

Mesh:

Year:  1992        PMID: 1534104

Source DB:  PubMed          Journal:  Instr Course Lect        ISSN: 0065-6895


  39 in total

1.  Transcript levels of major MMPs and ADAMTS-4 in relation to the clinicopathological profile of patients with lumbar disc herniation.

Authors:  Alexandros Tsarouhas; Giannoula Soufla; Pavlos Katonis; Dritan Pasku; Antonis Vakis; Demetrios A Spandidos
Journal:  Eur Spine J       Date:  2010-09-22       Impact factor: 3.134

Review 2.  Genetics of disc degeneration.

Authors:  Danny Chan; Youqiang Song; Pak Sham; Kenneth M C Cheung
Journal:  Eur Spine J       Date:  2006-07-04       Impact factor: 3.134

3.  Gender difference in genetic association between IL1A variant and early lumbar disc degeneration: a three-year follow-up.

Authors:  Pasi J Eskola; Per Kjaer; Joan S Sorensen; Annaleena Okuloff; Niels Wedderkopp; Iita Daavittila; Leena Ala-Kokko; Minna Männikkö; Jaro Karppinen
Journal:  Int J Mol Epidemiol Genet       Date:  2012-08-31

4.  Gender differences after lumbar sequestrectomy: a prospective clinical trial using quantitative sensory testing.

Authors:  Anja Tschugg; Wolfgang N Löscher; Sara Lener; Matthias Wildauer; Sebastian Hartmann; Sabrina Neururer; Claudius Thomé
Journal:  Eur Spine J       Date:  2016-12-21       Impact factor: 3.134

5.  Clinical and magnetic resonance imaging factors which may predict the need for surgery in lumbar disc herniation.

Authors:  Rouzbeh Motiei-Langroudi; Homa Sadeghian; Amir Saied Seddighi
Journal:  Asian Spine J       Date:  2014-08-19

6.  Pitting Oedema in a Patient with Lumbar Disc Herniation: Case report of an unusual association.

Authors:  Homa Sadeghian; Rouzbeh Motiei-Langroudi
Journal:  Sultan Qaboos Univ Med J       Date:  2018-01-10

7.  Risk factors for early reherniation after lumbar discectomy with or without annular closure: results of a multicenter randomized controlled study.

Authors:  Jenny C Kienzler; Javier Fandino; Erik Van de Kelft; Sandro Eustacchio; Gerrit Joan Bouma
Journal:  Acta Neurochir (Wien)       Date:  2020-10-21       Impact factor: 2.216

8.  Comparative analysis of serum proteomes: Identification of proteins associated with sciatica due to lumbar intervertebral disc herniation.

Authors:  Peigen Xie; Bin Liu; Ruiqiang Chen; Bu Yang; Jianwen Dong; Limin Rong
Journal:  Biomed Rep       Date:  2014-06-16

9.  What Are Long-term Predictors of Outcomes for Lumbar Disc Herniation? A Randomized and Observational Study.

Authors:  Dana Kerr; Wenyan Zhao; Jon D Lurie
Journal:  Clin Orthop Relat Res       Date:  2015-06       Impact factor: 4.176

10.  The role of intradiscal steroids in the treatment of discogenic low back pain.

Authors:  Stefan Muzin; Zacharia Isaac; Joseph Walker
Journal:  Curr Rev Musculoskelet Med       Date:  2008-06
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