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Literature DB >> 15340961

A flexible, palladium-catalyzed indole and azaindole synthesis by direct annulation of chloroanilines and chloroaminopyridines with ketones.

Marc Nazaré¹, Claudia Schneider, Andreas Lindenschmidt, David William Will.

Abstract

Entities: Chemical

Year: 2004 PMID： 15340961 DOI： 10.1002/anie.200460122

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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7 in total

1. Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A₂ Type X (sPLA₂-X) Inhibitors.

Authors: Laurent Knerr; Fabrizio Giordanetto; Peter Nordberg; Daniel Pettersen; Nidhal Selmi; Hans-Georg Beisel; Hannah de la Motte; Thomas Olsson; Tim D J Perkins; Margareta Herslöf; Åsa Månsson; Mikael Dahlström; Ingemar Starke; Johan Broddefalk; Gabrielle Saarinen; Fredrik Klingegård; Eva Hurt-Camejo; Birgitta Rosengren; Johan Brengdahl; Frank Jansen; Mattias Rohman; Jenny Sandmark; Kenth Hallberg; Tomas Åkerud; Robert G Roth; Marie Ahlqvist
Journal: ACS Med Chem Lett Date: 2018-06-23 Impact factor: 4.345

A flexible, palladium-catalyzed indole and azaindole synthesis by direct annulation of chloroanilines and chloroaminopyridines with ketones.

1. Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A₂ Type X (sPLA₂-X) Inhibitors.

2. Theoretical study of the regioselective cyclization of enaminones in the construction of benzofurans and indoles.

3. Multicomponent assembly of highly substituted indoles by dual palladium-catalyzed coupling reactions.

4. Microwave-assisted synthesis of 3-nitroindoles from N-aryl enamines via intramolecular arene-alkene coupling.

5. Direct Arylation of Benzo[b]furan and Other Benzo-Fused Heterocycles.

6. Bruceolline D: 3,3-dimethyl-1H,4H-cyclo-penta-[b]indol-2(3H)-one.

Review 7. Metal-Catalyzed Cross-Coupling Reactions on Azaindole Synthesis and Functionalization.

A flexible, palladium-catalyzed indole and azaindole synthesis by direct annulation of chloroanilines and chloroaminopyridines with ketones.

1. Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A2 Type X (sPLA2-X) Inhibitors.

2. Theoretical study of the regioselective cyclization of enaminones in the construction of benzofurans and indoles.

3. Multicomponent assembly of highly substituted indoles by dual palladium-catalyzed coupling reactions.

4. Microwave-assisted synthesis of 3-nitroindoles from N-aryl enamines via intramolecular arene-alkene coupling.

5. Direct Arylation of Benzo[b]furan and Other Benzo-Fused Heterocycles.

6. Bruceolline D: 3,3-dimethyl-1H,4H-cyclo-penta-[b]indol-2(3H)-one.

Review 7. Metal-Catalyzed Cross-Coupling Reactions on Azaindole Synthesis and Functionalization.

1. Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A₂ Type X (sPLA₂-X) Inhibitors.