Literature DB >> 15340427

Cancer chromosomes in crisis.

Ronald A DePinho, Kornelia Polyak.   

Abstract

The benign-to-malignant transition in human breast cancer is associated with a marked increase in chromosomal aberrations. A new study suggests that telomere dysfunction and its associated bridge-fusion-breakage cycles may drive this episodic instability, thereby providing aspiring cancer cells with the multiple genetic aberrations needed to achieve a fully malignant state.

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Year:  2004        PMID： 15340427     DOI： 10.1038/ng0904-932

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  36 in total

Review 1.  How to be good at being bad: centrosome amplification and mitotic propensity drive intratumoral heterogeneity.

Authors:  Padmashree C G Rida; Guilherme Cantuaria; Michelle D Reid; Omer Kucuk; Ritu Aneja
Journal:  Cancer Metastasis Rev       Date:  2015-12       Impact factor: 9.264

2.  Chromosomal translocation and segmental duplication in Cryptococcus neoformans.

Authors:  James A Fraser; Johnny C Huang; Read Pukkila-Worley; J Andrew Alspaugh; Thomas G Mitchell; Joseph Heitman
Journal:  Eukaryot Cell       Date:  2005-02

3.  c-Myc induces chromosomal rearrangements through telomere and chromosome remodeling in the interphase nucleus.

Authors:  Sherif F Louis; Bart J Vermolen; Yuval Garini; Ian T Young; Amanda Guffei; Zelda Lichtensztejn; Fabien Kuttler; Tony C Y Chuang; Sharareh Moshir; Virginie Mougey; Alice Y C Chuang; Paul Donald Kerr; Thierry Fest; Petra Boukamp; Sabine Mai
Journal:  Proc Natl Acad Sci U S A       Date:  2005-06-27       Impact factor: 11.205

Review 4.  Telomere dysfunction and tumour suppression: the senescence connection.

Authors:  Yibin Deng; Suzanne S Chan; Sandy Chang
Journal:  Nat Rev Cancer       Date:  2008-06       Impact factor: 60.716

5.  Significantly lengthened telomere in granulosa cells from women with polycystic ovarian syndrome (PCOS).

Authors:  Duo Wei; Juanke Xie; Baoli Yin; Haoying Hao; Xiaobing Song; Qi Liu; Cuilian Zhang; Yingpu Sun
Journal:  J Assist Reprod Genet       Date:  2017-05-13       Impact factor: 3.412

6.  Stem cell aging in the Drosophila ovary.

Authors:  Morris Waskar; Yishi Li; John Tower
Journal:  Age (Dordr)       Date:  2005-12-31

7.  A phase 2 study of the PARP inhibitor veliparib plus temozolomide in patients with heavily pretreated metastatic colorectal cancer.

Authors:  Michael J Pishvaian; Rebecca S Slack; Wei Jiang; A Ruth He; Jimmy J Hwang; Amy Hankin; Karen Dorsch-Vogel; Divyesh Kukadiya; Louis M Weiner; John L Marshall; Jonathan R Brody
Journal:  Cancer       Date:  2018-03-26       Impact factor: 6.860

8.  Novel patterns of genome rearrangement and their association with survival in breast cancer.

Authors:  James Hicks; Alexander Krasnitz; B Lakshmi; Nicholas E Navin; Michael Riggs; Evan Leibu; Diane Esposito; Joan Alexander; Jen Troge; Vladimir Grubor; Seungtai Yoon; Michael Wigler; Kenny Ye; Anne-Lise Børresen-Dale; Bjørn Naume; Ellen Schlicting; Larry Norton; Torsten Hägerström; Lambert Skoog; Gert Auer; Susanne Månér; Pär Lundin; Anders Zetterberg
Journal:  Genome Res       Date:  2006-12       Impact factor: 9.043

9.  Concurrent Veliparib With Chest Wall and Nodal Radiotherapy in Patients With Inflammatory or Locoregionally Recurrent Breast Cancer: The TBCRC 024 Phase I Multicenter Study.

Authors:  Reshma Jagsi; Kent A Griffith; Jennifer R Bellon; Wendy A Woodward; Janet K Horton; Alice Ho; Felix Y Feng; Corey Speers; Beth Overmoyer; Michael Sabel; Anne F Schott; Lori Pierce
Journal:  J Clin Oncol       Date:  2018-03-20       Impact factor: 44.544

Review 10.  Telomere maintenance and human bone marrow failure.

Authors:  Rodrigo T Calado; Neal S Young
Journal:  Blood       Date:  2008-01-31       Impact factor: 22.113
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