Literature DB >> 15340404

Cancer immunotherapy: breaking the barriers to harvest the crop.

Drew Pardoll1, James Allison.   

Abstract

Successful translation of modern molecular immunology into effective cancer immunotherapy is threatened by regulatory barriers and challenges to the development of novel agents and combinatorial strategies through effective public-private partnerships. For its promise to be fully realized, both the National Cancer Institute and Food and Drug Administration must take active steps to help academic investigators and companies jointly navigate the pathways from laboratory to clinic.

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Year:  2004        PMID: 15340404     DOI: 10.1038/nm0904-887

Source DB:  PubMed          Journal:  Nat Med        ISSN: 1078-8956            Impact factor:   53.440


  34 in total

1.  Chemotherapeutic agents enhance AAV2-mediated gene transfer into breast cancer cells promoting CD40 ligand-based immunotherapy.

Authors:  Bernd Koppold; Georg Sauer; Hildegard Buening; Michael Hallek; Rolf Kreienberg; Helmut Deissler; Christian Kurzeder
Journal:  J Cancer Res Clin Oncol       Date:  2006-06-23       Impact factor: 4.553

Review 2.  Incorporating tyrosine kinase inhibitors into treatment regimens for AML and ALL: is there a right or wrong way?

Authors:  Farhad Ravandi
Journal:  Curr Hematol Malig Rep       Date:  2014-06       Impact factor: 3.952

3.  A2A adenosine receptor protects tumors from antitumor T cells.

Authors:  Akio Ohta; Elieser Gorelik; Simon J Prasad; Franca Ronchese; Dmitriy Lukashev; Michael K K Wong; Xiaojun Huang; Sheila Caldwell; Kebin Liu; Patrick Smith; Jiang-Fan Chen; Edwin K Jackson; Sergey Apasov; Scott Abrams; Michail Sitkovsky
Journal:  Proc Natl Acad Sci U S A       Date:  2006-08-17       Impact factor: 11.205

4.  Isolation and optimization of murine IL-10 receptor blocking oligonucleotide aptamers using high-throughput sequencing.

Authors:  Alexey Berezhnoy; C Andrew Stewart; James O Mcnamara; William Thiel; Paloma Giangrande; Giorgio Trinchieri; Eli Gilboa
Journal:  Mol Ther       Date:  2012-03-20       Impact factor: 11.454

5.  Biomimetic Glyconanoparticle Vaccine for Cancer Immunotherapy.

Authors:  Eliran Moshe Reuven; Shani Leviatan Ben-Arye; Hai Yu; Roberto Duchi; Andrea Perota; Sophie Conchon; Shirley Bachar Abramovitch; Jean-Paul Soulillou; Cesare Galli; Xi Chen; Vered Padler-Karavani
Journal:  ACS Nano       Date:  2019-03-11       Impact factor: 15.881

Review 6.  Targeted therapies for renal cell carcinoma.

Authors:  Edwin M Posadas; Suwicha Limvorasak; Robert A Figlin
Journal:  Nat Rev Nephrol       Date:  2017-07-10       Impact factor: 28.314

7.  Opportunities and challenges in the development of experimental drug combinations for cancer.

Authors:  Rachel W Humphrey; Laura M Brockway-Lunardi; David T Bonk; Kathleen M Dohoney; James H Doroshow; Sandra J Meech; Mark J Ratain; Suzanne L Topalian; Drew M Pardoll
Journal:  J Natl Cancer Inst       Date:  2011-07-15       Impact factor: 13.506

Review 8.  Immunotherapy and immunoescape in colorectal cancer.

Authors:  Guillermo Mazzolini; Oihana Murillo; Catalina Atorrasagasti; Juan Dubrot; Iñigo Tirapu; Miguel Rizzo; Ainhoa Arina; Carlos Alfaro; Arantza Azpilicueta; Carmen Berasain; José L Perez-Gracia; Alvaro Gonzalez; Ignacio Melero
Journal:  World J Gastroenterol       Date:  2007-11-28       Impact factor: 5.742

9.  Targeting of antigens to B cells augments antigen-specific T-cell responses and breaks immune tolerance to tumor-associated antigen MUC1.

Authors:  Chuanlin Ding; Li Wang; Jose Marroquin; Jun Yan
Journal:  Blood       Date:  2008-07-31       Impact factor: 22.113

10.  The human cancer antigen mesothelin is more efficiently presented to the mouse immune system when targeted to the DEC-205/CD205 receptor on dendritic cells.

Authors:  Bei Wang; Janelle M Y Kuroiwa; Li-Zhen He; Anna Charalambous; Tibor Keler; Ralph M Steinman
Journal:  Ann N Y Acad Sci       Date:  2009-09       Impact factor: 5.691

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