OBJECTIVE: The purpose of the study was to characterize the perinatal outcome of pregnancies complicated by placenta accreta. METHODS: We conducted a case-control analysis of all deliveries between the years 1990 and 2000 that were complicated by placenta accreta. Perinatal variables included in the analysis were gestational age at delivery, birth weight, Apgar scores, and perinatal mortality. Statistical analysis was performed using both the unpaired and paired approach. P <.05 was considered significant. RESULTS: The study encompassed 34,450 deliveries, from which 310 cases of placenta accreta were diagnosed (0.9%) and compared with 310 matched controls. In the pregnancies complicated by placenta accreta, we found a statistically significant increase in preterm deliveries (10.7% versus 1%, P <.001, odds ratio 12.1, 95% confidence interval 3.7-39.9) and small-for-gestational-age babies (27.3% versus 14%, P <.001, odds ratio 5.05, 95% confidence interval 1.46-3.28). CONCLUSION: Pregnancies complicated by placenta accreta are at increased risk for perinatal adverse outcome. We speculate that these findings may arise from pathological implantation of the placenta, resulting in interference with normal fetal growth.
OBJECTIVE: The purpose of the study was to characterize the perinatal outcome of pregnancies complicated by placenta accreta. METHODS: We conducted a case-control analysis of all deliveries between the years 1990 and 2000 that were complicated by placenta accreta. Perinatal variables included in the analysis were gestational age at delivery, birth weight, Apgar scores, and perinatal mortality. Statistical analysis was performed using both the unpaired and paired approach. P <.05 was considered significant. RESULTS: The study encompassed 34,450 deliveries, from which 310 cases of placenta accreta were diagnosed (0.9%) and compared with 310 matched controls. In the pregnancies complicated by placenta accreta, we found a statistically significant increase in preterm deliveries (10.7% versus 1%, P <.001, odds ratio 12.1, 95% confidence interval 3.7-39.9) and small-for-gestational-age babies (27.3% versus 14%, P <.001, odds ratio 5.05, 95% confidence interval 1.46-3.28). CONCLUSION: Pregnancies complicated by placenta accreta are at increased risk for perinatal adverse outcome. We speculate that these findings may arise from pathological implantation of the placenta, resulting in interference with normal fetal growth.
Authors: Francesco Giurazza; Giuseppe Albano; Liliana Valentino; Emiliano Schena; Tiziana Capussela; Maria Antonella Di Pasquale; Francesco Di Pietto; Rosaria De Ritis; Gennaro Nasti; Giuseppe Scognamiglio; Raffaella Niola Journal: Radiol Med Date: 2017-07-29 Impact factor: 3.469
Authors: Felipe Moretti; Maria Merziotis; Zachary M Ferraro; Lawrence Oppenheimer; Karen Fung Kee Fung Journal: Case Rep Obstet Gynecol Date: 2014-06-01
Authors: Cynthia M Farquhar; Zhuoyang Li; Sarah Lensen; Claire McLintock; Wendy Pollock; Michael J Peek; David Ellwood; Marian Knight; Caroline Se Homer; Geraldine Vaughan; Alex Wang; Elizabeth Sullivan Journal: BMJ Open Date: 2017-10-05 Impact factor: 2.692
Authors: Nicole T Spillane; Stacy Zamudio; Jesus Alvarez-Perez; Tracy Andrews; Themba Nyirenda; Manuel Alvarez; Abdulla Al-Khan Journal: PLoS One Date: 2018-07-26 Impact factor: 3.240