Literature DB >> 15339657

Sculpting heart valves with NFATc and VEGF.

Diether Lambrechts1, Peter Carmeliet.   

Abstract

Heart valves are of vital importance for our moment-to-moment existence, but how they form remains a mystery. In this issue of Cell, Chang et al. reveal a novel role for calcineurin, NFATs, and VEGF in valve formation. Dynamic changes in NFAT/VEGF expression in regional myocardial and endocardial fields and developmental windows orchestrate this complex process.

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Year:  2004        PMID： 15339657     DOI： 10.1016/j.cell.2004.08.022

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  8 in total

Review 1.  Endothelial-cardiomyocyte interactions in cardiac development and repair.

Authors:  Patrick C H Hsieh; Michael E Davis; Laura K Lisowski; Richard T Lee
Journal:  Annu Rev Physiol       Date:  2006       Impact factor: 19.318

2.  Physiology of Cardiac Development: From Genetics to Signaling to Therapeutic Strategies.

Authors:  Cheng Sun; Maria I Kontaridis
Journal:  Curr Opin Physiol       Date:  2017-12-13

Review 3.  A change of heart: new roles for cilia in cardiac development and disease.

Authors:  Lydia Djenoune; Kathryn Berg; Martina Brueckner; Shiaulou Yuan
Journal:  Nat Rev Cardiol       Date:  2021-12-03       Impact factor: 49.421

4.  An excess of deleterious variants in VEGF-A pathway genes in Down-syndrome-associated atrioventricular septal defects.

Authors:  Christine Ackerman; Adam E Locke; Eleanor Feingold; Benjamin Reshey; Karina Espana; Janita Thusberg; Sean Mooney; Lora J H Bean; Kenneth J Dooley; Clifford L Cua; Roger H Reeves; Stephanie L Sherman; Cheryl L Maslen
Journal:  Am J Hum Genet       Date:  2012-10-05       Impact factor: 11.025

5.  Hypoxia-inducible transcription factor-1alpha triggers an autocrine survival pathway during embryonic cardiac outflow tract remodeling.

Authors:  Hongbin Liu; Steven A Fisher
Journal:  Circ Res       Date:  2008-05-08       Impact factor: 17.367

6.  Downregulation of calcineurin activity in cervical carcinoma.

Authors:  S Padma; A Pavani Sowjanya; Usha Rani Poli; Meenakshi Jain; Bn Rao; Gayatri Ramakrishna
Journal:  Cancer Cell Int       Date:  2005-04-01       Impact factor: 5.722

Review 7.  VEGF-A in Cardiomyocytes and Heart Diseases.

Authors:  Mariantonia Braile; Simone Marcella; Leonardo Cristinziano; Maria Rosaria Galdiero; Luca Modestino; Anne Lise Ferrara; Gilda Varricchi; Giancarlo Marone; Stefania Loffredo
Journal:  Int J Mol Sci       Date:  2020-07-26       Impact factor: 5.923

8.  Endocardial-to-mesenchymal transformation and mesenchymal cell colonization at the onset of human cardiac valve development.

Authors:  Michael G Monaghan; Miriam Linneweh; Simone Liebscher; Ben Van Handel; Shannon L Layland; Katja Schenke-Layland
Journal:  Development       Date:  2015-12-16       Impact factor: 6.868
  8 in total

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