Literature DB >> 15337725

Variations in rates of appropriate and inappropriate carotid endarterectomy for stroke prevention in 4 Canadian provinces.

James Kennedy1, Hude Quan, William A Ghali, Thomas E Feasby.   

Abstract

BACKGROUND: Carotid endarterectomy (CE), when performed on appropriate patients, reduces the incidence of stroke, yet there are marked variations in rates of this procedure. We sought to determine reasons for the variation in CE rates in 4 Canadian provinces.
METHODS: We identified all CEs performed in 4 Canadian provinces between January 2000 and December 2001, inclusive. From chart review and expert assessment, we determined the proportion of these procedures that were appropriate, inappropriate or of uncertain appropriateness, using the RAND/UCLA Appropriateness Method. We sought to determine the variation in rates by province and whether the variation was due to differences in type of hospital, surgical specialty or surgical volume.
RESULTS: Overall, 1656 (52.3%) of the 3167 CEs studied were performed for appropriate indications. The proportions of appropriate procedures were 78.2% (176/225) in Saskatchewan, 58.7% (481/819) in Alberta, 49.1% (350/713) in Manitoba and 46.0% (649/1410) in British Columbia (p < 0.001 across provinces). Rates of appropriate procedures per 100 000 population ranged from 44.3 in Manitoba to 16.2 in Saskatchewan (p < 0.001 across provinces). CEs were more likely to be appropriate when performed by a neurosurgeon compared with all other surgeons (74.4% v. 49.4% were appropriate; p < 0.001), when performed by surgeons doing fewer than 31 procedures over 2 years compared with surgeons doing more than 31 (70.1% v. 49.5% were appropriate; p < 0.001) and when performed in hospitals doing fewer than 135 procedures per year compared with hospitals doing more than 135 (63.4% v. 49.1% were appropriate; p < 0.001). Overall, 10.3% of procedures were done for inappropriate reasons.
INTERPRETATION: Our findings suggest some overuse (for inappropriate or uncertain indications) but also some underuse (low population rates in some regions). High rates of CE are associated with lower rates of appropriateness for both surgeons and hospitals. That 1 in 10 CEs is done inappropriately suggests the need for preoperative assessment of appropriateness.

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Year:  2004        PMID: 15337725      PMCID: PMC514641          DOI: 10.1503/cmaj.1040170

Source DB:  PubMed          Journal:  CMAJ        ISSN: 0820-3946            Impact factor:   8.262


  18 in total

1.  Geographic variation in the rate of carotid endarterectomy in Canada.

Authors:  T E Feasby; H Quan; W A Ghali
Journal:  Stroke       Date:  2001-10       Impact factor: 7.914

2.  Revisiting the appropriateness of carotid endarterectomy.

Authors:  Ethan A Halm; Mark R Chassin; Stanley Tuhrim; Larry H Hollier; A John Popp; Enrico Ascher; Herbert Dardik; Glenn Faust; Thomas S Riles
Journal:  Stroke       Date:  2003-05-08       Impact factor: 7.914

3.  A goodness-of-fit approach to inference procedures for the kappa statistic: confidence interval construction, significance-testing and sample size estimation.

Authors:  A Donner; M Eliasziw
Journal:  Stat Med       Date:  1992-08       Impact factor: 2.373

4.  A method for the detailed assessment of the appropriateness of medical technologies.

Authors:  R H Brook; M R Chassin; A Fink; D H Solomon; J Kosecoff; R E Park
Journal:  Int J Technol Assess Health Care       Date:  1986       Impact factor: 2.188

Review 5.  The appropriateness of carotid endarterectomy.

Authors:  C M Winslow; D H Solomon; M R Chassin; J Kosecoff; N J Merrick; R H Brook
Journal:  N Engl J Med       Date:  1988-03-24       Impact factor: 91.245

Review 6.  The appropriate use of carotid endarterectomy.

Authors:  Henry J M Barnett; Heather E Meldrum; Michael Eliasziw
Journal:  CMAJ       Date:  2002-04-30       Impact factor: 8.262

7.  Regional performance of carotid endarterectomy. Appropriateness, outcomes, and risk factors for complications.

Authors:  J H Wong; J M Findlay; M E Suarez-Almazor
Journal:  Stroke       Date:  1997-05       Impact factor: 7.914

8.  Analysis of pooled data from the randomised controlled trials of endarterectomy for symptomatic carotid stenosis.

Authors:  P M Rothwell; M Eliasziw; S A Gutnikov; A J Fox; D W Taylor; M R Mayberg; C P Warlow; H J M Barnett
Journal:  Lancet       Date:  2003-01-11       Impact factor: 79.321

9.  Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis.

Authors:  H J M Barnett; D W Taylor; R B Haynes; D L Sackett; S J Peerless; G G Ferguson; A J Fox; R N Rankin; V C Hachinski; D O Wiebers; M Eliasziw
Journal:  N Engl J Med       Date:  1991-08-15       Impact factor: 91.245

10.  Endarterectomy for asymptomatic carotid artery stenosis. Executive Committee for the Asymptomatic Carotid Atherosclerosis Study.

Authors: 
Journal:  JAMA       Date:  1995-05-10       Impact factor: 56.272

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1.  The inappropriate use of carotid endarterectomy.

Authors:  Henry J M Barnett
Journal:  CMAJ       Date:  2004-08-31       Impact factor: 8.262

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Journal:  CMAJ       Date:  2005-06-20       Impact factor: 8.262

3.  Management of MRI wait lists in Canada.

Authors:  Derek J Emery; Alan J Forster; Kaveh G Shojania; Stephanie Magnan; Michelle Tubman; Thomas E Feasby
Journal:  Healthc Policy       Date:  2009-02

4.  Core competencies in the science and practice of knowledge translation: description of a Canadian strategic training initiative.

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5.  Determinants of implementation of maternal health guidelines in Kosovo: mixed methods study.

Authors:  Sharon E Straus; Julia E Moore; Sami Uka; Christine Marquez; A Metin Gülmezoglu
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6.  The Council of Academic Hospitals of Ontario (CAHO) Adopting Research to Improve Care (ARTIC) Program: Reach, Sustainability, Spread and Lessons Learned from an Implementation Funding Model.

Authors:  Julia E Moore; Michelle Grouchy; Ian D Graham; Maureen Shandling; Winnie Doyle; Sharon E Straus
Journal:  Healthc Policy       Date:  2016-05

7.  Barriers, Facilitators and Priorities for Implementation of WHO Maternal and Perinatal Health Guidelines in Four Lower-Income Countries: A GREAT Network Research Activity.

Authors:  Joshua P Vogel; Julia E Moore; Caitlyn Timmings; Sobia Khan; Dina N Khan; Atkure Defar; Azmach Hadush; Marta Minwyelet Terefe; Luwam Teshome; Katherine Ba-Thike; Kyu Kyu Than; Ahmad Makuwani; Godfrey Mbaruku; Mwifadhi Mrisho; Kidza Yvonne Mugerwa; Lisa M Puchalski Ritchie; Shusmita Rashid; Sharon E Straus; A Metin Gülmezoglu
Journal:  PLoS One       Date:  2016-11-02       Impact factor: 3.240

8.  A knowledge synthesis of patient and public involvement in clinical practice guidelines: study protocol.

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Journal:  Implement Sci       Date:  2009-06-04       Impact factor: 7.327

9.  Developing a patient and family-centred approach for measuring the quality of injury care: a study protocol.

Authors:  Henry T Stelfox; Jamie M Boyd; Sharon E Straus; Anna R Gagliardi
Journal:  BMC Health Serv Res       Date:  2013-01-27       Impact factor: 2.655

10.  Appropriateness of the use of intravenous immune globulin before and after the introduction of a utilization control program.

Authors:  Thomas E Feasby; Hude Quan; Michelle Tubman; David Pi; Alan Tinmouth; Lawrence So; William A Ghali
Journal:  Open Med       Date:  2012-03-13
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