Literature DB >> 15337636

Anthroposophic therapies in chronic disease: the Anthroposophic Medicine Outcomes Study (AMOS).

Harald J Hamre1, C Becker-Witt, A Glockmann, R Ziegler, S N Willich, H Kiene.   

Abstract

CONTEXT: Anthroposophic medicine (AM) is used worldwide for chronic diseases.
OBJECTIVE: To study clinical outcomes and costs in patients treated with AM therapies for chronic conditions.
DESIGN: Prospective cohort study.
SETTING: 141 medical practices in Germany providing AM treatment. PARTICIPANTS AND
INTERVENTIONS: 898 outpatients aged 1-75 years referred to AM therapies (art, eurythmy or rhythmical massage, n = 665) or starting AM medical treatment (counselling, medicines, n = 233). MAIN OUTCOME MEASURES: Disease severity assessed independently by physician (Disease Score) and patient (Symptom Score), and health-related quality of life (SF-36, KINDL, KITA) after 3, 6, 12, 18, and 24 months; health costs in pre-study year and first study year.
RESULTS: Most common indications were mental disorders (32.0%), and musculoskeletal disorders (18.9%). Disease duration at baseline was median 3.0 years (interquartile range = i.q.r. 1.0-8.5, mean 6.5 +/- 8.4 years). Median number of AM therapy sessions was 12 (i.q.r. 10-20), median therapy duration was 120 days (i.q.r. 81-195). From baseline to 6-month follow-up, Disease Score (0-10) improved from 6.40 +/- 1.76 to 3.43 +/- 2.23 (p < 0.001), Symptom Score (0-10) improved from 5.89 +/- 1.75 to 3.35 +/- 2.09 (p < 0.001). In adults, SF-36 Physical Component Summary improved from mean 43.34 +/- 10.58 at baseline to 47.44 +/- 10.32 after 6 months (p < 0.001), SF-36 Mental Component Summary improved from 38.83 +/- 12.45 to 44.93 +/- 10.92 (p < 0.001). Similar HRQoL improvements were observed in children (KINDL, KITA). All improvements remained stable until 24-month follow-up. Adverse effects from AM therapies occurred in 2.7% (19/712) of patients. Three (0.5%) patients stopped therapy due to adverse effects. Health costs were 3,637 Euro per patient in the pre-study year and 3,484 Euro in the first study year, a decrease of 152 Euro (4.2%) per patient.
CONCLUSION: Anthroposophic therapies were associated with long-term reduction of chronic disease symptoms, improvement of health-related quality of life, and health cost reduction.

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Year:  2004        PMID: 15337636

Source DB:  PubMed          Journal:  Eur J Med Res        ISSN: 0949-2321            Impact factor:   2.175


  25 in total

1.  Use and safety of anthroposophic medications in chronic disease: a 2-year prospective analysis.

Authors:  Harald J Hamre; Claudia M Witt; Anja Glockmann; Wilfried Tröger; Stefan N Willich; Helmut Kiene
Journal:  Drug Saf       Date:  2006       Impact factor: 5.606

2.  Anthroposophic therapy for attention deficit hyperactivity: a two-year prospective study in outpatients.

Authors:  Harald J Hamre; Claudia M Witt; Gunver S Kienle; Christoph Meinecke; Anja Glockmann; Renatus Ziegler; Stefan N Willich; Helmut Kiene
Journal:  Int J Gen Med       Date:  2010-08-30

3.  Cost Analysis of Integrative Inpatient Treatment Based on DRG Data: The Example of Anthroposophic Medicine.

Authors:  Jürgen Heinz; Wolfgang Fiori; Peter Heusser; Thomas Ostermann
Journal:  Evid Based Complement Alternat Med       Date:  2013-01-31       Impact factor: 2.629

4.  Long-term outcomes of anthroposophic therapy for chronic low back pain: A two-year follow-up analysis.

Authors:  Harald J Hamre; Claudia M Witt; Gunver S Kienle; Anja Glockmann; Renatus Ziegler; Stefan N Willich; Helmut Kiene
Journal:  J Pain Res       Date:  2009-06-25       Impact factor: 3.133

5.  Outcome of anthroposophic medication therapy in chronic disease: a 12-month prospective cohort study.

Authors:  Harald J Hamre; Claudia M Witt; Anja Glockmann; Renatus Ziegler; Gunver S Kienle; Stefan N Willich; Helmut Kiene
Journal:  Drug Des Devel Ther       Date:  2009-02-06       Impact factor: 4.162

6.  Anthroposophic therapy for children with chronic disease: a two-year prospective cohort study in routine outpatient settings.

Authors:  Harald J Hamre; Claudia M Witt; Gunver S Kienle; Christoph Meinecke; Anja Glockmann; Stefan N Willich; Helmut Kiene
Journal:  BMC Pediatr       Date:  2009-06-19       Impact factor: 2.125

7.  Health costs in patients treated for depression, in patients with depressive symptoms treated for another chronic disorder, and in non-depressed patients: a two-year prospective cohort study in anthroposophic outpatient settings.

Authors:  Harald J Hamre; Claudia M Witt; Anja Glockmann; Renatus Ziegler; Gunver S Kienle; Stefan N Willich; Helmut Kiene
Journal:  Eur J Health Econ       Date:  2010-02

8.  Combined bias suppression in single-arm therapy studies.

Authors:  Harald J Hamre; Anja Glockmann; Gunver S Kienle; Helmut Kiene
Journal:  J Eval Clin Pract       Date:  2008-03-24       Impact factor: 2.431

9.  Inpatient treatment of community-acquired pneumonias with integrative medicine.

Authors:  Ulrich Geyer; Klas Diederich; Maria Kusserow; Andreas Laubersheimer; Klaus Kramer
Journal:  Evid Based Complement Alternat Med       Date:  2013-05-22       Impact factor: 2.629

10.  Long-term outcomes of anthroposophic treatment for chronic disease: a four-year follow-up analysis of 1510 patients from a prospective observational study in routine outpatient settings.

Authors:  Harald Johan Hamre; Helmut Kiene; Anja Glockmann; Renatus Ziegler; Gunver Sophia Kienle
Journal:  BMC Res Notes       Date:  2013-07-13
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