| Literature DB >> 15337256 |
Katarina Varnäs1, David R Thomas, Erkki Tupala, Jari Tiihonen, Håkan Hall.
Abstract
The distribution of the 5-HT7 receptor was analyzed using the selective 5-HT7 receptor antagonist radioligand [3H]SB-269970 and human brain whole hemisphere autoradiography. The results indicated that 5-HT7 receptors are most abundantly localized in the anterior thalamus and in the dentate gyrus. Other regions containing intermediate levels of 5-HT7 receptors included the hypothalamus, anterior cingulate gyrus, hippocampus, amygdala and certain brainstem nuclei. The distribution pattern obtained in this study supports the involvement of this receptor subtype in affective behavior and cognition.Entities:
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Year: 2004 PMID： 15337256 DOI： 10.1016/j.neulet.2004.06.025
Source DB: PubMed Journal: Neurosci Lett ISSN： 0304-3940 Impact factor: 3.046