Literature DB >> 15336984

TRPV6 and prostate cancer: cancer growth beyond the prostate correlates with increased TRPV6 Ca2+ channel expression.

Ulrich Wissenbach1, Barbara Niemeyer, Nina Himmerkus, Thomas Fixemer, Helmut Bonkhoff, Veit Flockerzi.   

Abstract

Life expectancy for patients suffering from prostate cancer is inversely correlated with the degree of extraprostatic metastasis. In order to find pharmacological tools to treat this aggressive growth it is important to define targets whose expression not only correlates with the malignancy of the cancerous cells, but that are also amenable to pharmacological intervention. In this review, we would like to focus on the potential role of a distinct class of ion channels that may be involved in this process. Copyright 2004 Elsevier Inc.

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Year:  2004        PMID: 15336984     DOI: 10.1016/j.bbrc.2004.08.042

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  39 in total

Review 1.  Role of TRP ion channels in cancer and tumorigenesis.

Authors:  George Shapovalov; Abigael Ritaine; Roman Skryma; Natalia Prevarskaya
Journal:  Semin Immunopathol       Date:  2016-02-03       Impact factor: 9.623

Review 2.  The epithelial calcium channels TRPV5 and TRPV6: regulation and implications for disease.

Authors:  Monique van Abel; Joost G J Hoenderop; René J M Bindels
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2005-04       Impact factor: 3.000

Review 3.  Specific detection and semi-quantitative analysis of TRPC4 protein expression by antibodies.

Authors:  Veit Flockerzi; Christine Jung; Thomas Aberle; Marcel Meissner; Marc Freichel; Stephan E Philipp; Wolfgang Nastainczyk; Patrick Maurer; Richard Zimmermann
Journal:  Pflugers Arch       Date:  2005-06-18       Impact factor: 3.657

4.  Cholesterol-induced activation of TRPM7 regulates cell proliferation, migration, and viability of human prostate cells.

Authors:  Yuyang Sun; Pramod Sukumaran; Archana Varma; Susan Derry; Abe E Sahmoun; Brij B Singh
Journal:  Biochim Biophys Acta       Date:  2014-04-25

5.  Pharmacological and functional properties of TRPM8 channels in prostate tumor cells.

Authors:  Maria Valero; Cruz Morenilla-Palao; Carlos Belmonte; Felix Viana
Journal:  Pflugers Arch       Date:  2010-11-05       Impact factor: 3.657

Review 6.  TRPV5 and TRPV6 in Ca(2+) (re)absorption: regulating Ca(2+) entry at the gate.

Authors:  Tom Nijenhuis; Joost G J Hoenderop; René J M Bindels
Journal:  Pflugers Arch       Date:  2005-07-26       Impact factor: 3.657

7.  Endogenous Voltage Potentials and the Microenvironment: Bioelectric Signals that Reveal, Induce and Normalize Cancer.

Authors:  Brook Chernet; Michael Levin
Journal:  J Clin Exp Oncol       Date:  2013

8.  Vanilloids induce oral cancer apoptosis independent of TRPV1.

Authors:  Cara B Gonzales; Nameer B Kirma; Jorge J De La Chapa; Richard Chen; Michael A Henry; Songjiang Luo; Kenneth M Hargreaves
Journal:  Oral Oncol       Date:  2014-01-14       Impact factor: 5.337

9.  TRPV6 calcium channel translocates to the plasma membrane via Orai1-mediated mechanism and controls cancer cell survival.

Authors:  Maylis Raphaël; V'yacheslav Lehen'kyi; Matthieu Vandenberghe; Benjamin Beck; Sergiy Khalimonchyk; Fabien Vanden Abeele; Leonardo Farsetti; Emmanuelle Germain; Alexandre Bokhobza; Adriana Mihalache; Pierre Gosset; Christoph Romanin; Philippe Clézardin; Roman Skryma; Natalia Prevarskaya
Journal:  Proc Natl Acad Sci U S A       Date:  2014-08-29       Impact factor: 11.205

10.  TRPV6 alleles do not influence prostate cancer progression.

Authors:  Thorsten Kessler; Ulrich Wissenbach; Rainer Grobholz; Veit Flockerzi
Journal:  BMC Cancer       Date:  2009-10-26       Impact factor: 4.430

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