Literature DB >> 15336810

Early and late clinical outcomes after primary stenting of the unprotected left main coronary artery stenosis in the setting of acute myocardial infarction.

Seung-Whan Lee1, Myeong-Ki Hong, Cheol Whan Lee, Young-Hak Kim, Jae-Hyeong Park, Jae-Hwan Lee, Ki-Hoon Han, Jae-Joong Kim, Seong-Wook Park, Seung-Jung Park.   

Abstract

BACKGROUND: Acute left main coronary artery occlusion is a dramatic condition with very high mortality. The study was aimed to evaluate the effect of primary stenting in patients with left main coronary artery (LMCA) disease in the setting of acute myocardial infarction (AMI).
METHODS: Between June 1997 and April 2002, primary stenting for left main coronary artery disease was performed in 18 patients with acute myocardial infarction. We evaluated early and late clinical outcomes, and prognostic determinants in this clinical setting.
RESULTS: Mean ages of patients were 59 +/- 12 years. Fourteen patients had cardiogenic shock on admission. Angiographic success (TIMI flow > or = 2 and diameter stenosis < 30% after stenting) was achieved in 17 patients (94%). In-hospital death occurred in eight patients (44%). Two patients (11%) received emergent bypass surgery because of hemodynamic instability after primary stenting. On univariate analysis, good pre-intervention TIMI flow (grade > or = 2) was identified as a good prognostic determinant of in-hospital survival. During mean follow-up of 39 +/- 22 months, there was no late death and one patient received bypass surgery. Probability of freedom from death at 3-year was 56 +/- 12%.
CONCLUSION: Primary stenting is a valuable therapeutic strategy for left main coronary disease in the setting of acute myocardial infarction, and it might save the life especially in patients with good pre-intervention TIMI flow (grade > or = 2). Long-term clinical outcome of patients surviving to hospital discharge is favorable. Copyright 2003 Elsevier Ireland Ltd.

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Year:  2004        PMID: 15336810     DOI: 10.1016/j.ijcard.2003.07.034

Source DB:  PubMed          Journal:  Int J Cardiol        ISSN: 0167-5273            Impact factor:   4.164


  9 in total

1.  Long-term prognosis of patients with acute myocardial infarction due to unprotected left main coronary artery disease: a single-centre experience over 14 years.

Authors:  Li Xu; Hao Sun; Le-Feng Wang; Xin-Chun Yang; Kui-Bao Li; Da-Peng Zhang; Hong-Shi Wang; Wei-Ming Li
Journal:  Singapore Med J       Date:  2016-07       Impact factor: 1.858

2.  Angioplasty of the left main coronary artery: Mid-term follow-up at University Medical Centre Groningen.

Authors:  W T Ruifrok; G A J Jessurun; R A Tio; F Zijlstra
Journal:  Neth Heart J       Date:  2005-10       Impact factor: 2.380

3.  High-risk percutaneous coronary intervention in the era of public reporting: clinical and ethical considerations in the care of an elderly patient with critical left main disease and shock.

Authors:  Beau M Hawkins; Lisa M Fitzgerald-McKeon; Robert W Yeh
Journal:  Circulation       Date:  2014-01-14       Impact factor: 29.690

4.  Predictors of survival following veno-arterial extracorporeal membrane oxygenation in patients with acute myocardial infarction-related refractory cardiogenic shock: clinical and coronary angiographic factors.

Authors:  Hyoung Soo Kim; Kyoung-Ha Park; Sang Ook Ha; Sun Hee Lee; Hong-Mi Choi; Sung-Ai Kim; Sunghoon Park; Sang Ho Jo; Hyun-Sook Kim; Sang Jin Han; Woo Jung Park
Journal:  J Thorac Dis       Date:  2020-05       Impact factor: 2.895

5.  Does stress hyperglycemia affect mortality? Acute myocardial infarction - case control study.

Authors:  Hayri Cinar; Akkan Avci; Muge Gulen; Begum Seyda Avci; Ertan Comertpay; Salim Satar
Journal:  Arch Med Sci Atheroscler Dis       Date:  2019-08-14

6.  New Predictors of Early and Late Outcomes after Primary Percutaneous Coronary Intervention in Patients with ST-Segment Elevation Myocardial Infarction and Unprotected Left Main Coronary Artery Culprit Lesion.

Authors:  Cãlin Homorodean; Adrian Corneliu Iancu; Daniel Leucuţa; Şerban Bãlãnescu; Ioana Mihaela Dregoesc; Mihai Spînu; Mihai Ober; Dan Tãtaru; Maria Olinic; Dan Bindea; Dan Olinic
Journal:  J Interv Cardiol       Date:  2019-03-18       Impact factor: 2.279

7.  Percutaneous Coronary Intervention After Return of Spontaneous Circulation Reduces the In-Hospital Mortality in Patients with Acute Myocardial Infarction Complicated by Cardiac Arrest.

Authors:  Jingcong Zhang; Haixia Xiong; Jie Chen; Qiuping Zou; Xiaoxing Liao; Yujie Li; Chunlin Hu
Journal:  Int J Gen Med       Date:  2021-10-28

8.  N-Acetylcysteine effects on transforming growth factor-β and tumor necrosis factor-α serum levels as pro-fibrotic and inflammatory biomarkers in patients following ST-segment elevation myocardial infarction.

Authors:  Azita Hajhossein Talasaz; Hossein Khalili; Yaser Jenab; Mojtaba Salarifar; Mohammad Ali Broumand; Farzad Darabi
Journal:  Drugs R D       Date:  2013-09

9.  Primary Angioplasty in a Catastrophic Presentation: Acute Left Main Coronary Total Occlusion-The ATOLMA Registry.

Authors:  A Gutiérrez-Barrios; L Gheorghe; S Camacho-Freire; F Valencia-Serrano; D Cañadas-Pruaño; G Calle-Pérez; I Alarcón de la Lastra; E Silva; D García-Molinero; A Agarrado-Luna; R Zayas-Ruedas; R Vázquez-García; A Serra
Journal:  J Interv Cardiol       Date:  2020-07-27       Impact factor: 2.279

  9 in total

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