Literature DB >> 15336735

Primary malignant tumours of bone and soft tissue in the elderly.

M Buchner1, L Bernd, A Zahlten-Hinguranage, D Sabo.   

Abstract

AIMS: This study reports outcome, functional results and quality of life of 45 elderly patients with age over 70 after surgery for primary malignant bone and soft tissue tumours.
METHODS: There were 24 primary malignant bone tumours and 21 soft tissue sarcomas. The most frequent diagnoses were: chondrosarcoma, malignant fibrous histiocytoma and liposarcoma. Local tumour resection with and without osteosynthesis, endoprostheses, and amputations had been performed for surgery. The patients were prospectively followed in a tumour register.
RESULTS: Complication and revision rate, functional outcome using the Musculoskeletal Tumor Society score, 5-year survival rate, median survival time and quality of life according to the Life Satisfaction Index A and the global health and quality-of-life scale of the QLQ-C30 revealed results that are only slightly inferior to those reported in younger tumour patients.
CONCLUSIONS: The results of this study generally justify even extensive tumour surgery in the elderly patient over 70 although outcomes are not quite as good as those reported for younger adults. However, especially in the old patient indications like general condition and comorbidity should be given due consideration before any decision is made on whether surgery should be performed and if so what surgical technique should be applied.

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Year:  2004        PMID: 15336735     DOI: 10.1016/j.ejso.2004.06.013

Source DB:  PubMed          Journal:  Eur J Surg Oncol        ISSN: 0748-7983            Impact factor:   4.424


  7 in total

1.  What is the effect of advanced age and comorbidity on postoperative morbidity and mortality after musculoskeletal tumor surgery?

Authors:  Koichi Ogura; Hideo Yasunaga; Hiromasa Horiguchi; Kiyohide Fushimi; Hirotaka Kawano
Journal:  Clin Orthop Relat Res       Date:  2014-08-20       Impact factor: 4.176

2.  External-beam radiation therapy combined with limb-sparing surgery in elderly patients (>70 years) with primary soft tissue sarcomas of the extremities : A retrospective analysis.

Authors:  Claudia Andrä; Alexander Klein; Hans Roland Dürr; Josefine Rauch; Lars Hartwin Lindner; Thomas Knoesel; Martin Angele; Andrea Baur-Melnyk; Claus Belka; Falk Roeder
Journal:  Strahlenther Onkol       Date:  2017-02-22       Impact factor: 3.621

3.  The prognostic significance of surgical treatment for excessive elderly patients with soft tissue sarcoma.

Authors:  Hiroyuki Tsuchie; Makoto Emori; Hiroyuki Nagasawa; Naohisa Miyakoshi; Yasutaka Murahashi; Emi Mizushima; Toshihiko Yamashita; Yoichi Shimada
Journal:  Int J Clin Oncol       Date:  2018-02-27       Impact factor: 3.402

4.  Descriptive epidemiology and outcomes of bone sarcomas in adolescent and young adult patients in Japan.

Authors:  Takashi Fukushima; Koichi Ogura; Toru Akiyama; Katsushi Takeshita; Akira Kawai
Journal:  BMC Musculoskelet Disord       Date:  2018-08-18       Impact factor: 2.362

5.  Worse Survival in Elderly Patients with Extremity Soft-Tissue Sarcoma.

Authors:  Miriam L Hoven-Gondrie; Esther Bastiaannet; Vincent K Y Ho; Barbara L van Leeuwen; Gerrit-Jan Liefers; Harald J Hoekstra; Albert J H Suurmeijer
Journal:  Ann Surg Oncol       Date:  2016-03-08       Impact factor: 5.344

6.  Clinical features and outcomes of primary bone and soft tissue sarcomas in adolescents and young adults.

Authors:  Kazuhiko Hashimoto; Shunji Nishimura; Naohiro Oka; Masao Akagi
Journal:  Mol Clin Oncol       Date:  2020-02-04

Review 7.  Unravelling the heterogeneity of soft tissue and bone sarcoma patients' health-related quality of life: a systematic literature review with focus on tumour location.

Authors:  Dide den Hollander; Winette T A Van der Graaf; Marco Fiore; Bernd Kasper; Susanne Singer; Ingrid M E Desar; Olga Husson
Journal:  ESMO Open       Date:  2020-10
  7 in total

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