Literature DB >> 15335663

Screening and determination of methamphetamine and amphetamine in the blood, urine and stomach contents in emergency medical care and autopsy cases.

T Takayasu1, T Ohshima, J Nishigami, T Kondo, T Nagano.   

Abstract

Methamphetamine (MA) and amphetamine (AMP) were screened and their levels were determined using the Toxi-Lab thin-layer chromatography system and gas chromatography-mass spectrometry, respectively, in the blood, urine and stomach contents from 211 emergency medical care and 417 autopsy cases. MA and AMP were detected in 5 emergency medical cases, and the blood MA and AMP concentrations ranged from 0.697-0.041 micromol/100 g and from 0.0944-0.0003 micromol/100 g, respectively. MA and AMP were detected in 19 autopsy cases, in which blood MA and AMP concentration ranged from 14.3-0.123 micromol/100 g and from 0.256-0.0017 micromol/100 g, respectively. The autopsy cases included 5 cases of sudden death with blood MA concentration of less than 3 micromol/100 g. MA and AMP screening and determination in emergency medical care and autopsy cases provide useful information and are indispenable in clarifying the dimensions of MA abuse in Japan.

Entities:  

Year:  1995        PMID: 15335663     DOI: 10.1016/1353-1131(95)90036-5

Source DB:  PubMed          Journal:  J Clin Forensic Med        ISSN: 1353-1131


  14 in total

1.  Nanoparticle based galectin-1 gene silencing, implications in methamphetamine regulation of HIV-1 infection in monocyte derived macrophages.

Authors:  Jessica L Reynolds; Wing Cheung Law; Supriya D Mahajan; Ravikumar Aalinkeel; Bindukumar Nair; Donald E Sykes; Ken-Tye Yong; Rui Hui; Paras N Prasad; Stanley A Schwartz
Journal:  J Neuroimmune Pharmacol       Date:  2012-06-12       Impact factor: 4.147

Review 2.  Modulation of intracellular restriction factors contributes to methamphetamine-mediated enhancement of acquired immune deficiency syndrome virus infection of macrophages.

Authors:  Xu Wang; Yizhong Wang; Li Ye; Jieliang Li; Yu Zhou; Sinem Sakarcan; Wenzhe Ho
Journal:  Curr HIV Res       Date:  2012-07       Impact factor: 1.581

3.  Methamphetamine causes mitrochondrial oxidative damage in human T lymphocytes leading to functional impairment.

Authors:  Raghava Potula; Brian J Hawkins; Jonathan M Cenna; Shongshan Fan; Holly Dykstra; Servio H Ramirez; Brenda Morsey; Michael R Brodie; Yuri Persidsky
Journal:  J Immunol       Date:  2010-07-28       Impact factor: 5.422

4.  Methamphetamine facilitates HIV infection of primary human monocytes through inhibiting cellular viral restriction factors.

Authors:  Yu Liu; Feng-Zhen Meng; Xu Wang; Peng Wang; Jin-Biao Liu; Wen-Hui Hu; Won-Bin Young; Wen-Zhe Ho
Journal:  Cell Biosci       Date:  2021-11-10       Impact factor: 7.133

5.  Methamphetamine enhances HIV-1 infectivity in monocyte derived dendritic cells.

Authors:  Madhavan P N Nair; Zainulabedin M Saiyed; Narayanan Nair; Nimisha H Gandhi; Jose W Rodriguez; Nawal Boukli; Elias Provencio-Vasquez; Robert M Malow; Maria Jose Miguez-Burbano
Journal:  J Neuroimmune Pharmacol       Date:  2008-10-29       Impact factor: 4.147

6.  Methamphetamine enhances HIV infection of macrophages.

Authors:  Hao Liang; Xu Wang; Hui Chen; Li Song; Li Ye; Shi-Hong Wang; Yan-Jian Wang; Lin Zhou; Wen-Zhe Ho
Journal:  Am J Pathol       Date:  2008-05-05       Impact factor: 4.307

7.  Proteomic analyses of the effects of drugs of abuse on monocyte-derived mature dendritic cells.

Authors:  Jessica L Reynolds; Supriya D Mahajan; Ravikunar Aalinkeel; B Nair; Donald E Sykes; Stanley A Schwartz
Journal:  Immunol Invest       Date:  2009       Impact factor: 3.657

8.  Proteomic analyses of methamphetamine (METH)-induced differential protein expression by immature dendritic cells (IDC).

Authors:  Jessica L Reynolds; Supriya D Mahajan; Donald E Sykes; Stanley A Schwartz; Madhavan P N Nair
Journal:  Biochim Biophys Acta       Date:  2007-02-13

9.  Methamphetamine modulates DC-SIGN expression by mature dendritic cells.

Authors:  Madhavan P N Nair; Supriya Mahajan; Don Sykes; Meghana V Bapardekar; Jessica L Reynolds
Journal:  J Neuroimmune Pharmacol       Date:  2006-06-23       Impact factor: 4.147

10.  Modulation of the proteome of peripheral blood mononuclear cells from HIV-1-infected patients by drugs of abuse.

Authors:  Jessica L Reynolds; Supriya D Mahajan; Ravikunar Aalinkeel; Bindukumar Nair; Donald E Sykes; Anardi Agosto-Mujica; Chiu Bin Hsiao; Stanley A Schwartz
Journal:  J Clin Immunol       Date:  2009-06-20       Impact factor: 8.317

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