Literature DB >> 15332711

Immunomodulating activity of rifampicin.

H M Ziglam1, I Daniels, R G Finch.   

Abstract

It has been shown that some antibiotics can modify cytokine production. We have examined the effect of rifampicin on secretion of interleukin-1beta (IL-1beta), IL-6, IL-10, and tumor necrosis factor alpha (TNF-alpha) by lipopolysaccharide (LPS)-stimulated or heat killed staphylococci (Pansorbin) stimulated monocytes. Secretion of IL-1beta and TNF-a were significantly inhibited (P<0.002) whereas secretion of IL-6 and IL-10 were significantly increased (P<0.003) by rifampicin treated mononuclear cells. Rifampicin had immunomodulatory effects through its capacity to alter the secretion of tested cytokines by human monocytes.

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Year:  2004        PMID: 15332711     DOI: 10.1179/joc.2004.16.4.357

Source DB:  PubMed          Journal:  J Chemother        ISSN: 1120-009X            Impact factor:   1.714


  20 in total

1.  Effect of rifampin on production of inflammatory mediators in HepG2 liver epithelial cells.

Authors:  Yael Yuhas; Eva Berent; Shai Ashkenazi
Journal:  Antimicrob Agents Chemother       Date:  2011-09-19       Impact factor: 5.191

Review 2.  Antibiotic therapy for Crohn's disease: a review.

Authors:  Simon Lal; A Hillary Steinhart
Journal:  Can J Gastroenterol       Date:  2006-10       Impact factor: 3.522

Review 3.  An Update on Medical Treatment Options for Hidradenitis Suppurativa.

Authors:  I E Deckers; E P Prens
Journal:  Drugs       Date:  2016-02       Impact factor: 9.546

4.  Hepatocyte-protective and anti-oxidant effects of rifampicin on human chronic hepatitis C and murine acute hepatocyte disorder.

Authors:  Kazuhiro Kataoka; Yutaka Kono; Masanobu Sugimoto; Yasuhiro Furuichi; Masayoshi Shichiri; Yujiro Tanaka
Journal:  Exp Ther Med       Date:  2010-09-29       Impact factor: 2.447

Review 5.  The critical role of macrophages in the pathogenesis of hidradenitis suppurativa.

Authors:  Ahmed Shah; Raed Alhusayen; Saeid Amini-Nik
Journal:  Inflamm Res       Date:  2017-06-27       Impact factor: 4.575

6.  Oral antimycobacterial therapy in chronic cutaneous sarcoidosis: a randomized, single-masked, placebo-controlled study.

Authors:  Wonder P Drake; Kyra Oswald-Richter; Bradley W Richmond; Joan Isom; Victoria E Burke; Holly Algood; Nicole Braun; Thyneice Taylor; Kusum V Pandit; Caroline Aboud; Chang Yu; Naftali Kaminski; Alan S Boyd; Lloyd E King
Journal:  JAMA Dermatol       Date:  2013-09       Impact factor: 10.282

7.  Rifampin inhibits prostaglandin E2 production and arachidonic acid release in human alveolar epithelial cells.

Authors:  Yael Yuhas; Inbar Azoulay-Alfaguter; Eva Berent; Shai Ashkenazi
Journal:  Antimicrob Agents Chemother       Date:  2007-10-01       Impact factor: 5.191

8.  Roles of NF-kappaB activation and peroxisome proliferator-activated receptor gamma inhibition in the effect of rifampin on inducible nitric oxide synthase transcription in human lung epithelial cells.

Authors:  Yael Yuhas; Eva Berent; Regev Cohen; Shai Ashkenazi
Journal:  Antimicrob Agents Chemother       Date:  2008-12-29       Impact factor: 5.191

9.  Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain.

Authors:  Xiaohui Wang; Peter M Grace; Michael N Pham; Kui Cheng; Keith A Strand; Christina Smith; Jing Li; Linda R Watkins; Hang Yin
Journal:  FASEB J       Date:  2013-04-08       Impact factor: 5.191

Review 10.  Do pulmonary findings of granulomatosis with polyangiitis respond to anti-tuberculosis treatment?

Authors:  Döndü Üsküdar Cansu; Nilgün Işıksalan Özbülbül; Gülsüm Akyol; Deniz Arık; Cengiz Korkmaz
Journal:  Rheumatol Int       Date:  2018-04-09       Impact factor: 2.631

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