| Literature DB >> 15331236 |
Abstract
Formation of synapses by neurons onto specific targets is essential to the function of a nervous system. The isolation and analysis of Caenorhabditis elegans and Drosophila mutants with synaptogenesis defects has provided insight into the functions of evolutionarily conserved molecules at single-synapse resolution. Importantly, such studies have uncovered novel molecules and signaling mechanisms. Here, recent progress on synaptic target recognition and synaptic assembly are reviewed.Entities:
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Year: 2004 PMID: 15331236 DOI: 10.1016/j.tins.2004.07.003
Source DB: PubMed Journal: Trends Neurosci ISSN: 0166-2236 Impact factor: 13.837