Literature DB >> 15327046

Bladder and sexual function among women with multiple sclerosis.

Diane Borello-France1, Wendy Leng, Margie O'Leary, Macrina Xavier, Janet Erickson, Michael B Chancellor, Tracy W Cannon.   

Abstract

OBJECTIVE: Genitourinary dysfunction is common in women with multiple sclerosis (MS), yet few studies have evaluated the association between bladder and sexual dysfunction in these women. The aim of this study was to determine factors, including demographic and bladder function, associated with sexual dysfunction in a sample of women with MS.
METHODS: One hundred and thirty-three women with MS completed questionnaires related to overall heath status, bladder function and sexual function. Response frequencies and percentages were calculated for questionnaire responses. Multivariate logistic regression analyses were performed to determine predictors of sexual dysfunction.
RESULTS: Sixty-one per cent of the sample indicated that they had a problem with bladder control. Forty-seven per cent of respondents indicated that their neurological problems interfered with their sex life. Over 70% of the sample reported that they enjoyed, felt aroused and experienced orgasm during sexual activity. Not having a sexual partner and the indication of bothersome neurological problems were the best predictors of sexual dysfunction. Interestingly, patients bothered by their urge incontinence had higher levels of orgasm compared to women not bothered by urge incontinence.
CONCLUSIONS: Although over half of the women reported voiding symptoms, most still enjoyed, felt aroused and could experience orgasm. Neurological symptoms and lacking a sexual partner emerged as the best predictors of sexual dysfunction. Urge incontinence may not be a risk factor for an orgasm. Our findings elucidate the complex nature of sexual dysfunction in women with MS.

Entities:  

Mesh:

Year:  2004        PMID: 15327046     DOI: 10.1191/1352458504ms1060oa

Source DB:  PubMed          Journal:  Mult Scler        ISSN: 1352-4585            Impact factor:   6.312


  22 in total

Review 1.  Evaluation of lower urinary tract symptoms in multiple sclerosis patients: Review of the literature and current guidelines.

Authors:  Shachar Moshe Aharony; Ornella Lam; Jacques Corcos
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Review 2.  Multiple sclerosis and sexual dysfunction.

Authors:  Zhen-Ni Guo; Si-Yuan He; Hong-Liang Zhang; Jiang Wu; Yi Yang
Journal:  Asian J Androl       Date:  2012-03-26       Impact factor: 3.285

3.  Connective tissue and its growth factor CTGF distinguish the morphometric and molecular remodeling of the bladder in a model of neurogenic bladder.

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4.  The urinary bladder of spontaneously hypertensive rat demonstrates bladder hypertrophy, inflammation, and fibrosis but not hyperplasia.

Authors:  Shanwei Shen; Chun-Mei Xia; Li-Ya Qiao
Journal:  Life Sci       Date:  2014-10-30       Impact factor: 5.037

5.  Symptomatic therapy in multiple sclerosis.

Authors:  Teresa C Frohman; Wanda Castro; Anjali Shah; Ardith Courtney; Jeffrey Ortstadt; Scott L Davis; Diana Logan; Thomas Abraham; Jaspreet Abraham; Gina Remington; Katherine Treadaway; Donna Graves; John Hart; Olaf Stuve; Gary Lemack; Benjamin Greenberg; Elliot M Frohman
Journal:  Ther Adv Neurol Disord       Date:  2011-03       Impact factor: 6.570

6.  Quality of life in multiple sclerosis patients with urinary disorders: reliability and validity of the Turkish version of King's Health Questionnaire.

Authors:  Yeşim Akkoc; Hale Karapolat; Sibel Eyigor; Hilal Yesil; Nur Yüceyar
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7.  The prevalence of urinary catheterization in women and men with multiple sclerosis.

Authors:  Sangeeta T Mahajan; Heidi E Frasure; Ruth Ann Marrie
Journal:  J Spinal Cord Med       Date:  2013-04-12       Impact factor: 1.985

8.  Prevalence of Sexual Dysfunction in Women with Multiple Sclerosis: a Systematic Review and Meta-Analysis.

Authors:  Amirreza Azimi; Sara Hanaei; Mohammad Ali Sahraian; Mehdi Mohammadifar; Sreeram V Ramagopalan; Mahsa Ghajarzadeh
Journal:  Maedica (Buchar)       Date:  2019-12

9.  Coronavirus-induced demyelination of neural pathways triggers neurogenic bladder overactivity in a mouse model of multiple sclerosis.

Authors:  Matthew T McMillan; Xiao-Qing Pan; Ariana L Smith; Diane K Newman; Susan R Weiss; Michael R Ruggieri; Anna P Malykhina
Journal:  Am J Physiol Renal Physiol       Date:  2014-07-09

10.  Sexual problems among women with multiple sclerosis.

Authors:  Effat Merghati-Khoei; Kowsar Qaderi; Leila Amini; Jeffrey E Korte
Journal:  J Neurol Sci       Date:  2013-06-10       Impact factor: 3.181

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