| Literature DB >> 15326348 |
Cally Roper1, Richard Pearce, Shalini Nair, Brian Sharp, François Nosten, Tim Anderson.
Abstract
Here we present molecular evidence demonstrating that malaria parasites bearing high-level pyrimethamine resistance originally arrived in Africa from southeast Asia. The resistance alleles carried by these migrants are now spreading across Africa at an alarming rate, signaling the end of affordable malaria treatment and presenting sub-Saharan Africa with a public health crisis.Entities:
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Year: 2004 PMID: 15326348 DOI: 10.1126/science.1098876
Source DB: PubMed Journal: Science ISSN: 0036-8075 Impact factor: 47.728