Literature DB >> 15325934

Effects of edaravone on reperfusion injury in patients with acute myocardial infarction.

Kenichi Tsujita1, Hideki Shimomura, Hiroaki Kawano, Jun Hokamaki, Masaya Fukuda, Takuro Yamashita, Satoru Hida, Yoshinori Nakamura, Yasuhiro Nagayoshi, Tomohiro Sakamoto, Michihiro Yoshimura, Hidekazu Arai, Hisao Ogawa.   

Abstract

This clinical pilot study was a randomized, controlled, open-label study in 80 patients with acute myocardial infarction and was designed to examine the effects of a novel free radical scavenger, edaravone. Administration of edaravone before myocardial reperfusion was associated with smaller enzymatic infarcts and better clinical outcome.

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Year:  2004        PMID: 15325934     DOI: 10.1016/j.amjcard.2004.05.007

Source DB:  PubMed          Journal:  Am J Cardiol        ISSN: 0002-9149            Impact factor:   2.778


  26 in total

1.  A novel method for inducing focal ischemia in vitro.

Authors:  Marc J P Richard; Tarek M Saleh; Bouchaib El Bahh; Jeffrey A Zidichouski
Journal:  J Neurosci Methods       Date:  2010-04-22       Impact factor: 2.390

2.  Efficacy of edaravone on coronary artery bypass patients with myocardial damage after ischemia and reperfusion: a meta analysis.

Authors:  Chenhong Zheng; Shouying Liu; Peiliang Geng; Huiming Zhang; Hongpeng Zhang; Airong Tang; Xiaohua Xie
Journal:  Int J Clin Exp Med       Date:  2015-02-15

3.  Scavenging free radicals improves endothelial dysfunction in human coronary arteries in vivo.

Authors:  Jun-ichi Oyama; Shinji Satoh; Nobuhiro Suematsu; Toshiaki Kadokami; Toyoki Maeda; Masahiro Sugano; Naoki Makino
Journal:  Heart Vessels       Date:  2010-07-31       Impact factor: 2.037

4.  Edaravone prevents neurotoxicity of mutant L166P DJ-1 in Parkinson's disease.

Authors:  Bing Li; Dawei Yu; Zhiying Xu
Journal:  J Mol Neurosci       Date:  2013-05-10       Impact factor: 3.444

Review 5.  Formulary Drug Review: Edaravone.

Authors:  Zaynah K Ali; Danial E Baker
Journal:  Hosp Pharm       Date:  2017-10-09

6.  Edaravone protects rats against oxidative stress and apoptosis in experimentally induced myocardial infarction: Biochemical and ultrastructural evidence.

Authors:  Md Quamrul Hassan; Md Sayeed Akhtar; M Akhtar; Javed Ali; Syed Ehtaishamul Haque; Abul Kalam Najmi
Journal:  Redox Rep       Date:  2015-04-20       Impact factor: 4.412

Review 7.  Reactive oxygen species in cardiovascular disease.

Authors:  Koichi Sugamura; John F Keaney
Journal:  Free Radic Biol Med       Date:  2011-05-15       Impact factor: 7.376

8.  Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia.

Authors:  David A Brown; Sharon L Hale; Christopher P Baines; Carlos L del Rio; Robert L Hamlin; Yukie Yueyama; Anusak Kijtawornrat; Steve T Yeh; Chad R Frasier; Luke M Stewart; Fatiha Moukdar; Saame Raza Shaikh; Kelsey H Fisher-Wellman; P Darrell Neufer; Robert A Kloner
Journal:  J Cardiovasc Pharmacol Ther       Date:  2013-11-28       Impact factor: 2.457

Review 9.  Cardiac dysfunction and oxidative stress in the metabolic syndrome: an update on antioxidant therapies.

Authors:  Olesya Ilkun; Sihem Boudina
Journal:  Curr Pharm Des       Date:  2013       Impact factor: 3.116

10.  Beyond free radical scavenging: Beneficial effects of edaravone (Radicut) in various diseases (Review).

Authors:  Kiyoshi Kikuchi; Nobuyuki Takeshige; Naoki Miura; Yoko Morimoto; Takashi Ito; Salunya Tancharoen; Kei Miyata; Chiemi Kikuchi; Narumi Iida; Hisaaki Uchikado; Naohisa Miyagi; Naoto Shiomi; Terukazu Kuramoto; Ikuro Maruyama; Motohiro Morioka; Ko-Ichi Kawahara
Journal:  Exp Ther Med       Date:  2011-09-20       Impact factor: 2.447

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