Literature DB >> 15324992

The General Movements in children with Down syndrome.

Luigi Mazzone1, Diego Mugno, Domenico Mazzone.   

Abstract

OBJECTIVE: Aim of our study was to describe the character of General Movements (GMs) in children with Down Syndrome (DS).
MATERIAL AND METHODS: GMs of 23 children with DS and of 30 healthy full-term infants were assessed from birth to 6th month corrected age. A qualitative and a semi-quantitative evaluation of GMs were achieved for each child. Data were graphically displayed to obtain growth curves of motor optimality scores.
RESULTS: GMs in children with DS are characterised by low-low/moderate speed, large-large/moderate amplitude, partially creating impression of fluency, smoothness and complexity, abrupt beginning and end, few other concurrent gross movements. During the 6 months, all children showed an improvement of qualitative and semi-quantitative evaluation, but it was possible to observe great heterogeneity among children in the evolutionary course. GMs evaluation of children with no known motor problems was normal, showing only slight and transient abnormalities at first months.
CONCLUSION: GMs character of children with DS could be related to central nervous system and peripheral abnormalities characterizing this syndrome. The evaluation of GMs in children with DS could be an early marker of motor impairment and help in early management decisions making.

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Mesh:

Year:  2004        PMID: 15324992     DOI: 10.1016/j.earlhumdev.2004.04.013

Source DB:  PubMed          Journal:  Early Hum Dev        ISSN: 0378-3782            Impact factor:   2.079


  8 in total

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2.  The exercise redox paradigm in the Down's syndrome: improvements in motor function and increases in blood oxidative status in young adults.

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3.  The motor repertoire in 3- to 5-month old infants with Down syndrome.

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Review 4.  A Novel Way to Measure and Predict Development: A Heuristic Approach to Facilitate the Early Detection of Neurodevelopmental Disorders.

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5.  Gross motor proficiency and intellectual functioning: A comparison among children with Down syndrome, children with borderline intellectual functioning, and typically developing children.

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7.  General movements in genetic disorders: A first look into Cornelia de Lange syndrome.

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Review 8.  Building an adaptive brain across development: targets for neurorehabilitation must begin in infancy.

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  8 in total

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