Literature DB >> 1532460

Cost-effectiveness analysis of extended conservative therapy versus surgical intervention in the management of herniated lumbar intervertebral disc.

L Shvartzman1, E Weingarten, H Sherry, S Levin, A Persaud.   

Abstract

The management of herniated lumbar intervertebral disc for patients not responding to an initial trial of conservative therapy is generally surgical. Little is known about the effect of continued conservative therapy on patients who have not improved or have deteriorated within the first 3 months. This study assessed which form of treatment, surgical or continued conservative therapy, is more cost-effective once an adequate trial of conservative therapy has failed. The study is a retrospective chart review of 55 white male truck drivers who presented with acutely herniated nucleus pulposus between 1985 and 1989. Twenty-five patients underwent surgery, and 30 underwent continued conservative therapy after initial rehabilitation. No significant difference was found in outcome (80% good or fair in both the surgical and conservative groups) or costs ($55,000 +/- $1,000/case during a 5-year period), hence no difference in the cost-effectiveness between the two treatment modalities (each $63,000 +/- $2,000/adjusted outcome). Conservatively treated patients, however, missed significantly more work. It was concluded that, for a patient not responding to the initial trial of conservative therapy, the option to undergo continued conservative treatment should be made available.

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Year:  1992        PMID: 1532460     DOI: 10.1097/00007632-199202000-00010

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  13 in total

1.  Centralization in patients with sciatica: are pain responses to repeated movement and positioning associated with outcome or types of disc lesions?

Authors:  Hanne B Albert; Eva Hauge; Claus Manniche
Journal:  Eur Spine J       Date:  2011-09-23       Impact factor: 3.134

Review 2.  Molecular therapy of the intervertebral disc.

Authors:  S Tim Yoon; Nilpesh M Patel
Journal:  Eur Spine J       Date:  2006-07-12       Impact factor: 3.134

3.  The impact of workers' compensation on outcomes of surgical and nonoperative therapy for patients with a lumbar disc herniation: SPORT.

Authors:  Steven J Atlas; Tor D Tosteson; Emily A Blood; Jonathan S Skinner; Glenn S Pransky; James N Weinstein
Journal:  Spine (Phila Pa 1976)       Date:  2010-01-01       Impact factor: 3.468

Review 4.  Toward an understanding of the role of notochordal cells in the adult intervertebral disc: from discord to accord.

Authors:  Makarand V Risbud; Thomas P Schaer; Irving M Shapiro
Journal:  Dev Dyn       Date:  2010-08       Impact factor: 3.780

5.  Defining the phenotype of young healthy nucleus pulposus cells: recommendations of the Spine Research Interest Group at the 2014 annual ORS meeting.

Authors:  Makarand V Risbud; Zachary R Schoepflin; Fackson Mwale; Rita A Kandel; Sibylle Grad; James C Iatridis; Daisuke Sakai; Judith A Hoyland
Journal:  J Orthop Res       Date:  2015-01-21       Impact factor: 3.494

6.  Microdiscectomy Is More Cost-effective Than a 6-Month Nonsurgical Care Regimen for Chronic Radiculopathy.

Authors:  R Andrew Glennie; Jennifer C Urquhart; Prosper Koto; Parham Rasoulinejad; David Taylor; Keith Sequeira; Thomas Miller; Jim Watson; Richard Rosedale; Stewart I Bailey; Kevin R Gurr; Fawaz Siddiqi; Christopher S Bailey
Journal:  Clin Orthop Relat Res       Date:  2022-03-01       Impact factor: 4.755

7.  Design of the Spine Patient outcomes Research Trial (SPORT).

Authors:  Nancy J O Birkmeyer; James N Weinstein; Anna N A Tosteson; Tor D Tosteson; Jonathan S Skinner; Jon D Lurie; Richard Deyo; John E Wennberg
Journal:  Spine (Phila Pa 1976)       Date:  2002-06-15       Impact factor: 3.468

8.  Biologic response of degenerative living human nucleus pulposus cells to treatment with cytokines.

Authors:  Sang Hyun Kim; Sung Uk Kuh; Keung Nyun Kim; Jeong Yoon Park; Ki Hong Cho; Dong Kyu Chin; Keun Su Kim; Yong Eun Cho
Journal:  Yonsei Med J       Date:  2015-01       Impact factor: 2.759

9.  Structural brain alterations in patients with lumbar disc herniation: a preliminary study.

Authors:  Michael Luchtmann; Yvonne Steinecke; Sebastian Baecke; Ralf Lützkendorf; Johannes Bernarding; Jana Kohl; Boris Jöllenbeck; Claus Tempelmann; Patrick Ragert; Raimund Firsching
Journal:  PLoS One       Date:  2014-03-03       Impact factor: 3.240

Review 10.  Enhancing intervertebral disc repair and regeneration through biology: platelet-rich plasma as an alternative strategy.

Authors:  Shan-Zheng Wang; Yun-Feng Rui; Qi Tan; Chen Wang
Journal:  Arthritis Res Ther       Date:  2013       Impact factor: 5.156

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