Literature DB >> 15322059

Parameters of the attenuated schistosome vaccine evaluated in the olive baboon.

Thomas M Kariuki1, Idle O Farah, Dorcas S Yole, Jason M Mwenda, Govert J Van Dam, André M Deelder, R Alan Wilson, Patricia S Coulson.   

Abstract

Five exposures of baboons to the attenuated schistosome vaccine gave greater protection than three exposures, but this attenuation was not sustained when challenge was delayed. Within the scope of the data collected, fecal egg counts and circulating antigen levels did not accurately predict the observed worm burdens. Levels of immunoglobulin G at challenge correlated best with protection, but there was little evidence of a recall response.

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Year:  2004        PMID： 15322059      PMCID： PMC517471          DOI： 10.1128/IAI.72.9.5526-5529.2004

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  15 in total

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Authors:  K Polman; M M Diakhate; D Engels; S Nahimana; G J Van Dam; S T Falcão Ferreira; A M Deelder; B Gryseels
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3.  Quality control of Kato slide counts for Schistosoma mansoni: a review of 12 years' experience in Kenya.

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Journal:  Am J Trop Med Hyg       Date:  1989-03       Impact factor: 2.345

5.  Ultrastructural localization of the circulating anodic antigen in the digestive tract of Schistosoma mansoni using monoclonal antibodies in an immunogold labeling procedure.

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Journal:  Am J Trop Med Hyg       Date:  1986-05       Impact factor: 2.345

6.  Schistosoma mansoni in the Kenyan baboon (Papio anubis): the development and predictability of resistance to homologous challenge.

Authors:  R F Sturrock; A E Butterworth; V Houba; S D Karamsadkar; R Kimani
Journal:  Trans R Soc Trop Med Hyg       Date:  1978       Impact factor: 2.184

7.  Schistosoma mansoni in the baboon (Papio anubis): parasitological responses of Kenyan baboons to different exposures of a local parasite strain.

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Journal:  Parasitol Today       Date:  1999-12

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Authors:  R F Sturrock
Journal:  J Med Primatol       Date:  1986       Impact factor: 0.667
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  22 in total

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Review 6.  Immune effector mechanisms against schistosomiasis: looking for a chink in the parasite's armour.

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7.  Schistosoma mansoni tetraspanning orphan receptor (SmTOR): a new vaccine candidate against schistosomiasis.

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9.  Protective and antifecundity effects of Sm-p80-based DNA vaccine formulation against Schistosoma mansoni in a nonhuman primate model.

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