| Literature DB >> 15322043 |
Isabella Vlisidou1, Mark Lyte, Pauline M van Diemen, Pippa Hawes, Paul Monaghan, Timothy S Wallis, Mark P Stevens.
Abstract
The role of the neuroendocrine environment in the pathogenesis of enteric bacterial infections is increasingly being recognized. Here we report that norepinephrine augments Escherichia coli O157:H7-induced intestinal inflammatory and secretory responses as well as bacterial adherence to intestinal mucosa in a bovine ligated ileal loop model of infection. Norepinephrine modulation of enteritis and adherence was dependent on the ability of E. coli O157:H7 to form attaching and effacing lesions.Entities:
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Year: 2004 PMID: 15322043 PMCID: PMC517440 DOI: 10.1128/IAI.72.9.5446-5451.2004
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441