BACKGROUND: For a given blood pressure, the risk of death from coronary artery disease is much higher in northern Europe and the United States than in Mediterranean countries. OBJECTIVE: In this prospective cohort study, we tested the hypothesis that regular wine drinking reduces the hypertension-related risk of death. DESIGN: We used data from 36 583 healthy middle-aged men who had normal results on an electrocardiogram and were not taking drugs for cardiovascular disease risk factors. The subjects underwent a comprehensive health appraisal at the Center for Preventive Medicine between 1 January 1978 and 31 December 1985. Mortality from all causes and from specific causes during a 13-21-y follow-up was recorded. RESULTS: In a Cox model adjusted for 6 confounding variables, moderate wine drinkers (those who consumed <60 g alcohol/d and no beer) with systolic blood pressure (SBP) of 158, 139, or 116 mm Hg had significantly lower risks of death from all causes by 23%, 27%, and 37%, respectively, than did abstainers. Even for the highest quartile of blood pressure, moderate wine drinkers were protected from all-cause mortality. No significant reduction in all-cause mortality in relation to SBP was observed in other drinkers (those who consumed > or =60 g alcohol/d or who consumed beer and wine). CONCLUSION: A moderate intake of wine is associated with a lower risk of mortality from all causes in persons with hypertension.
BACKGROUND: For a given blood pressure, the risk of death from coronary artery disease is much higher in northern Europe and the United States than in Mediterranean countries. OBJECTIVE: In this prospective cohort study, we tested the hypothesis that regular wine drinking reduces the hypertension-related risk of death. DESIGN: We used data from 36 583 healthy middle-aged men who had normal results on an electrocardiogram and were not taking drugs for cardiovascular disease risk factors. The subjects underwent a comprehensive health appraisal at the Center for Preventive Medicine between 1 January 1978 and 31 December 1985. Mortality from all causes and from specific causes during a 13-21-y follow-up was recorded. RESULTS: In a Cox model adjusted for 6 confounding variables, moderate wine drinkers (those who consumed <60 g alcohol/d and no beer) with systolic blood pressure (SBP) of 158, 139, or 116 mm Hg had significantly lower risks of death from all causes by 23%, 27%, and 37%, respectively, than did abstainers. Even for the highest quartile of blood pressure, moderate wine drinkers were protected from all-cause mortality. No significant reduction in all-cause mortality in relation to SBP was observed in other drinkers (those who consumed > or =60 g alcohol/d or who consumed beer and wine). CONCLUSION: A moderate intake of wine is associated with a lower risk of mortality from all causes in persons with hypertension.
Authors: Chayakrit Krittanawong; Ameesh Isath; Robert S Rosenson; Muzamil Khawaja; Zhen Wang; Sonya E Fogg; Salim S Virani; Lu Qi; Yin Cao; Michelle T Long; Christy C Tangney; Carl J Lavie Journal: Am J Med Date: 2022-05-14 Impact factor: 5.928
Authors: Christiana Aryee; William K B A Owiredu; James Osei-Yeboah; Ellis Owusu-Dabo; Edwin F Laing; Isaac K Owusu Journal: Int J Hypertens Date: 2016-09-27 Impact factor: 2.420