OBJECTIVE: To assess trends in the prevalence of HIV infection among voluntary counseling and testing (VCT) clients in Uganda and to describe the utility of VCT data for monitoring the HIV epidemic in 1992-2000. METHODS: We analyzed routinely collected data from first-time VCT clients not reporting illness as a reason for testing. We developed a model adjusting for test site, couple testing, and premarital testing, assessed trends in adjusted prevalence of HIV infection and shifts in age-specific peak prevalence, and compared antenatal clinic (ANC) surveillance data and VCT prevalence trends. RESULTS: Among 201,741 clients, adjusted prevalence of HIV infection declined from 23% in 1992 to 13% in 2000 (P < 0.001) (men, 17%-9% [P < 0.001]; women, 31%-18% [P < 0.001]). The prevalence declined for all age groups except men older than 39 years and women older than 34 years. The prevalence increased for women older than 39 years (P < 0.003). Between 1992 and 2000, peak prevalence declined for both men (31% to 24%) and women (44% to 41%), whereas the age at which the peak occurred increased for both men (36 to 41 years) and women (31 to 36 years). VCT and ANC prevalence trends were similar. CONCLUSION: In Uganda, the prevalence of HIV infection among male and female VCT clients declined from 1992 to 2000, similar to ANC surveillance data, but did not decline in older age groups. In regions with well-established VCT programs, VCT data may provide a useful and convenient tool for monitoring the HIV epidemic.
OBJECTIVE: To assess trends in the prevalence of HIV infection among voluntary counseling and testing (VCT) clients in Uganda and to describe the utility of VCT data for monitoring the HIV epidemic in 1992-2000. METHODS: We analyzed routinely collected data from first-time VCT clients not reporting illness as a reason for testing. We developed a model adjusting for test site, couple testing, and premarital testing, assessed trends in adjusted prevalence of HIV infection and shifts in age-specific peak prevalence, and compared antenatal clinic (ANC) surveillance data and VCT prevalence trends. RESULTS: Among 201,741 clients, adjusted prevalence of HIV infection declined from 23% in 1992 to 13% in 2000 (P < 0.001) (men, 17%-9% [P < 0.001]; women, 31%-18% [P < 0.001]). The prevalence declined for all age groups except men older than 39 years and women older than 34 years. The prevalence increased for women older than 39 years (P < 0.003). Between 1992 and 2000, peak prevalence declined for both men (31% to 24%) and women (44% to 41%), whereas the age at which the peak occurred increased for both men (36 to 41 years) and women (31 to 36 years). VCT and ANC prevalence trends were similar. CONCLUSION: In Uganda, the prevalence of HIV infection among male and female VCT clients declined from 1992 to 2000, similar to ANC surveillance data, but did not decline in older age groups. In regions with well-established VCT programs, VCT data may provide a useful and convenient tool for monitoring the HIV epidemic.
Authors: Tom Oluoch; Ibrahim Mohammed; Rebecca Bunnell; Reinhard Kaiser; Andrea A Kim; Anthony Gichangi; Mary Mwangi; Sufia Dadabhai; Lawrence Marum; Alloys Orago; Jonathan Mermin Journal: Open AIDS J Date: 2011-12-30
Authors: Alemnesh H Mirkuzie; Mitike Molla Sisay; Sven Gudmund Hinderaker; Karen Marie Moland; Odd Mørkve Journal: BMC Public Health Date: 2012-12-26 Impact factor: 3.295
Authors: Jairam R Lingappa; Barrot Lambdin; Elizabeth Ann Bukusi; Kenneth Ngure; Linda Kavuma; Mubiana Inambao; William Kanweka; Susan Allen; James N Kiarie; Joseph Makhema; Edwin Were; Rachel Manongi; David Coetzee; Guy de Bruyn; Sinead Delany-Moretlwe; Amalia Magaret; Nelly Mugo; Andrew Mujugira; Patrick Ndase; Connie Celum Journal: PLoS One Date: 2008-01-09 Impact factor: 3.240