BACKGROUND: Low implantation rates in stimulated IVF cycles may be related to suboptimal endometrial perfusion. Endometrial and subendometrial blood flow was compared between stimulated and natural cycles in the same patients undergoing IVF. METHODS: Three-dimensional (3D) ultrasound examination with power Doppler was performed in stimulated and natural cycles of 67 consecutive patients to measure endometrial thickness, uterine artery pulsatility index/resistance index, endometrial volume, vascularization index (VI)/flow index (FI)/vascularization flow index (VFI) of endometrial and subendometrial regions. RESULTS: Endometrial and subendometrial blood flow was absent in four (6.0%) patients in the stimulated cycle and two (3.0%) patients in the natural cycle. Endometrial and subendometrial VI/FI/VFI were significantly lower in stimulated cycles than those in natural cycles. The median (95% CI) decreases in endometrial VI/FI/VFI were 35.8% (-2.5, 216.8), 5.0% (0.1, 12.3) and 48.4% (2.5, 315.3) respectively whereas the corresponding decreases in the subendometrial region were 66.6% (-0.2, 220.5), 4.3% (0.8, 16.2) and 76.3% (41.0, 303.4) respectively. CONCLUSION: Endometrial and subendometrial blood flow was significantly lower in the stimulated cycle than that in the natural cycle.
BACKGROUND: Low implantation rates in stimulated IVF cycles may be related to suboptimal endometrial perfusion. Endometrial and subendometrial blood flow was compared between stimulated and natural cycles in the same patients undergoing IVF. METHODS: Three-dimensional (3D) ultrasound examination with power Doppler was performed in stimulated and natural cycles of 67 consecutive patients to measure endometrial thickness, uterine artery pulsatility index/resistance index, endometrial volume, vascularization index (VI)/flow index (FI)/vascularization flow index (VFI) of endometrial and subendometrial regions. RESULTS: Endometrial and subendometrial blood flow was absent in four (6.0%) patients in the stimulated cycle and two (3.0%) patients in the natural cycle. Endometrial and subendometrial VI/FI/VFI were significantly lower in stimulated cycles than those in natural cycles. The median (95% CI) decreases in endometrial VI/FI/VFI were 35.8% (-2.5, 216.8), 5.0% (0.1, 12.3) and 48.4% (2.5, 315.3) respectively whereas the corresponding decreases in the subendometrial region were 66.6% (-0.2, 220.5), 4.3% (0.8, 16.2) and 76.3% (41.0, 303.4) respectively. CONCLUSION: Endometrial and subendometrial blood flow was significantly lower in the stimulated cycle than that in the natural cycle.
Authors: N Pereira; R T Elias; P J Christos; A C Petrini; K Hancock; J P Lekovich; Z Rosenwaks Journal: Hum Reprod Date: 2017-07-01 Impact factor: 6.918
Authors: Eman Omran; Mohamed El-Sharkawy; Akmal El-Mazny; Mohamed Hammam; Wafaa Ramadan; Dina Latif; Dalia Samir; Sherine Sobh Journal: Int J Womens Health Date: 2018-04-04
Authors: Maria C Magnus; Allen J Wilcox; Elin A Fadum; Håkon K Gjessing; Signe Opdahl; Petur B Juliusson; Liv Bente Romundstad; Siri E Håberg Journal: Hum Reprod Date: 2021-03-18 Impact factor: 6.918
Authors: Margaux Anav; Simon Phillips; Alice Ferrieres-Hoa; Anna Gala; Alice Fournier; Claire Vincens; Emmanuelle Vintejoux; Elsa Maris; Camille Grysole; François Bissonnette; Sophie Brouillet; Isaac Jacques Kadoch; Samir Hamamah Journal: Sci Rep Date: 2019-09-16 Impact factor: 4.379