Literature DB >> 15317230

Breakthrough in treating gestational diabetes mellitus.

Gideon Koren.   

Abstract

QUESTION: I practise in a remote community in Manitoba. Quite a few of my patients experience gestational diabetes. Their compliance with the insulin regimen is abysmal. Can I give them an oral medication? ANSWER: Recent studies have indicated that glyburide does not cross the human placenta and that its effectiveness and safety profiles are similar to those of insulin.

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Year:  2004        PMID： 15317230      PMCID： PMC2214626     

Source DB:  PubMed          Journal:  Can Fam Physician        ISSN： 0008-350X            Impact factor:   3.275


  6 in total

1.  A comparison of glyburide and insulin in women with gestational diabetes mellitus.

Authors:  O Langer; D L Conway; M D Berkus; E M Xenakis; O Gonzales
Journal:  N Engl J Med       Date:  2000-10-19       Impact factor: 91.245

Review 2.  Maternal-fetal transport of hypoglycaemic drugs.

Authors:  Facundo Garcia-Bournissen; Denice S Feig; Gideon Koren
Journal:  Clin Pharmacokinet       Date:  2003       Impact factor: 6.447

3.  Comparative placental transport of oral hypoglycemic agents in humans: a model of human placental drug transfer.

Authors:  B D Elliott; S Schenker; O Langer; R Johnson; T Prihoda
Journal:  Am J Obstet Gynecol       Date:  1994-09       Impact factor: 8.661

4.  Gestational diabetes mellitus: compliance with testing.

Authors:  Robert G Moses; Alison J Webb; Christine D Comber; John G Walton; Keith J Coleman; Warren S Davis; Clive J McCosker
Journal:  Aust N Z J Obstet Gynaecol       Date:  2003-12       Impact factor: 2.100

5.  Resistance exercise decreases the need for insulin in overweight women with gestational diabetes mellitus.

Authors:  Gabrielle N Brankston; B F Mitchell; Edmond A Ryan; Nanette B Okun
Journal:  Am J Obstet Gynecol       Date:  2004-01       Impact factor: 8.661

Review 6.  Epidemiology of gestational diabetes mellitus and its association with Type 2 diabetes.

Authors:  A Ben-Haroush; Y Yogev; M Hod
Journal:  Diabet Med       Date:  2004-02       Impact factor: 4.359
  6 in total

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