Literature DB >> 15316794

Corneal sensation after laser epithelial keratomileusis for the correction of myopia.

Wolfgang Artur Herrmann1, Chirag Shah, Bernhard Gabler, Christoph Winkler von Mohrenfels, K Hufendiek, Chris Patrick Lohmann.   

Abstract

BACKGROUND: Subepithelial nerve fibre bundles and stromal nerves are damaged during laser epithelial keratomileusis (LASEK). The aim of this study was to investigate the recovery of corneal sensation after LASEK for the correction of myopia.
METHODS: Corneal sensation was evaluated in 40 eyes of 20 patients using a Cochet-Bonnet aesthesiometer before surgery and 3 days, 14 days, 1, 3 and 6 months after LASEK for the correction of mild to moderate myopia (range -2.5 D to -8.0 D). At every examination corneal sensation was tested in the apex of the cornea and in one point each at the 12, 3, 6 and 9 o' clock positions 2 mm from the centre of the cornea.
RESULTS: Corneal sensation was significantly reduced at 3 days and 14 days after surgery (P<0.01). The loss of corneal sensation was greatest 3 days after surgery and corneal sensation increased during the first month after LASEK. After 1 month, 3 months and 6 months no significant difference was found between preoperative and postoperative sensation. There was no significant difference in sensation between different areas of the cornea after LASEK.
CONCLUSIONS: Corneal nerves are disrupted during LASEK surgery and the procedure results in a significant reduction in corneal sensation. During the first month after surgery the depressed corneal sensation improved and subsequently went back to preoperative values, staying stable 3 months and 6 months after surgery.

Entities:  

Mesh:

Year:  2004        PMID: 15316794     DOI: 10.1007/s00417-004-0974-z

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN: 0721-832X            Impact factor:   3.117


  17 in total

1.  Tear secretion following spherical and astigmatic excimer laser photorefractive keratectomy.

Authors:  D S Siganos; C N Popescu; C S Siganos; G Pistola
Journal:  J Cataract Refract Surg       Date:  2000-11       Impact factor: 3.351

2.  Morphology of corneal nerves using confocal microscopy.

Authors:  L Oliveira-Soto; N Efron
Journal:  Cornea       Date:  2001-05       Impact factor: 2.651

Review 3.  Corneal nerves: structure, contents and function.

Authors:  Linda J Müller; Carl F Marfurt; Friedrich Kruse; Timo M T Tervo
Journal:  Exp Eye Res       Date:  2003-05       Impact factor: 3.467

4.  Effect of beam variables on corneal sensitivity after excimer laser photorefractive keratectomy.

Authors:  J G Lawrenson; M C Corbett; D P O'Brart; J Marshall
Journal:  Br J Ophthalmol       Date:  1997-08       Impact factor: 4.638

5.  Laser-assisted subepithelial keratectomy for myopia: two-year follow-up.

Authors:  Rudolf Autrata; Jaroslav Rehurek
Journal:  J Cataract Refract Surg       Date:  2003-04       Impact factor: 3.351

6.  In vivo human corneal confocal microscopy of identical fields of subepithelial nerve plexus, basal epithelial, and wing cells at different times.

Authors:  B R Masters; A A Thaer
Journal:  Microsc Res Tech       Date:  1994-12-01       Impact factor: 2.769

7.  Evaluation of subjective assessments and objective diagnostic tests for diagnosing tear-film disorders known to cause ocular irritation.

Authors:  S C Pflugfelder; S C Tseng; O Sanabria; H Kell; C G Garcia; C Felix; W Feuer; B L Reis
Journal:  Cornea       Date:  1998-01       Impact factor: 2.651

8.  Laser in situ keratomileusis-induced (presumed) neurotrophic epitheliopathy.

Authors:  S E Wilson
Journal:  Ophthalmology       Date:  2001-06       Impact factor: 12.079

9.  [Excimer laser subepithelial ablation (ELSA) or laser epithelial keratomileusis (LASEK) - a new kerato-refractive procedure for myopia. Surgical technique and first clinical results on 24 eyes and 3 months follow-up].

Authors:  Chris P Lohmann; Christoph Winkler Von Mohrenfels; Bernhard Gabler; Wolfgang Hermann; Michael Müller
Journal:  Klin Monbl Augenheilkd       Date:  2002 Jan-Feb       Impact factor: 0.700

10.  Mechanical vs. alcohol epithelial removal during photorefractive keratectomy.

Authors:  F Carones; T Fiore; R Brancato
Journal:  J Refract Surg       Date:  1999 Sep-Oct       Impact factor: 3.573

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  3 in total

1.  Tear film function and corneal sensation in the early postoperative period after LASEK for the correction of myopia.

Authors:  Wolfgang Artur Herrmann; Chirag Pradip Shah; Christoph Winkler von Mohrenfels; Bernhard Gabler; Karsten Hufendiek; Chris Patrick Lohmann
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2005-04-15       Impact factor: 3.117

Review 2.  In Vivo Confocal Microscopy of Corneal Nerves in Health and Disease.

Authors:  Andrea Cruzat; Yureeda Qazi; Pedram Hamrah
Journal:  Ocul Surf       Date:  2016-10-19       Impact factor: 5.033

Review 3.  Corneal nerves in health and disease.

Authors:  Brittany Simmons Shaheen; May Bakir; Sandeep Jain
Journal:  Surv Ophthalmol       Date:  2014-01-23       Impact factor: 6.048

  3 in total

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