| Literature DB >> 1531629 |
Abstract
The alpha 5 beta 1, alpha 6 beta 4 and Mac-1 integrins all participate in the endocytotic cycle. By contrast, alpha 3 beta 1, alpha 4 beta 1 and LFA-1 do so much more slowly, or not at all, in the cell lines examined. This indicates that the alpha-chains appear to determine whether an integrin cycles or not, and that alpha 5 beta 1, alpha 6 beta 4 and Mac-1 can be brought to the leading edge of a moving cell by endocytosis and recycling.Entities:
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Year: 1992 PMID: 1531629 PMCID: PMC556468 DOI: 10.1002/j.1460-2075.1992.tb05068.x
Source DB: PubMed Journal: EMBO J ISSN: 0261-4189 Impact factor: 11.598