Literature DB >> 15316124

The NOAR Damaged Joint Count (NOAR-DJC): a clinical measure for assessing articular damage in patients with early inflammatory polyarthritis including rheumatoid arthritis.

D K Bunn1, L Shepstone, L M Galpin, N J Wiles, D P M Symmons.   

Abstract

OBJECTIVES: To evaluate the reliability and validity of the Norfolk Arthritis Register Damaged Joint Count (NOAR-DJC) in patients with early inflammatory polyarthritis (IP).
METHODS: The NOAR-DJC examines deformity in 51 joints. Deformity is defined as inability to adopt the anatomical position, reduction in range of movement by at least one-third, and/or surgical alteration of the joint. Reliability was investigated by assessing intra- and inter-observer agreement in 40 and 32 patients, respectively. Validity was assessed by correlating the NOAR-DJC with the eroded joint count (criterion validity), the Health Assessment Questionnaire (HAQ) (convergent construct validity) and tender and swollen joint counts (divergent construct validity) and by discriminating between those who did and did not satisfy criteria for rheumatoid arthritis (discriminant validity).
RESULTS: The intraclass correlation coefficient for the intra- and inter-rater studies were 0.88 [95% confidence interval (CI) 0.79, 0.94, P<0.00001] and 0.74 (95% CI 0.53, 0.86, P<0.00001), respectively. Correlations with eroded joint counts and HAQ scores after 5 yr follow-up were r(s) = 0.42 (95% CI 0.35, 0.49, P<0.01) and r(s) = 0.45 (95% CI 0.4, 0.5, P<0.01), respectively. Correlations with tender and swollen joint counts were weak (r(s) = 0.28 and r(s) = 0.33).
CONCLUSION: The NOAR-DJC is a quick, reliable and valid tool for assessing articular damage in patients with early IP.

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Year:  2004        PMID: 15316124     DOI: 10.1093/rheumatology/keh372

Source DB:  PubMed          Journal:  Rheumatology (Oxford)        ISSN: 1462-0324            Impact factor:   7.580


  4 in total

1.  HLA-Cw6 and HLA-DRB1*07 together are associated with less severe joint disease in psoriatic arthritis.

Authors:  Pauline Y P C Ho; Anne Barton; Jane Worthington; Wendy Thomson; Alan J Silman; Ian N Bruce
Journal:  Ann Rheum Dis       Date:  2007-01-12       Impact factor: 19.103

2.  Multinational evidence-based recommendations on how to investigate and follow-up undifferentiated peripheral inflammatory arthritis: integrating systematic literature research and expert opinion of a broad international panel of rheumatologists in the 3E Initiative.

Authors:  P Machado; I Castrejon; W Katchamart; R Koevoets; B Kuriya; M Schoels; L Silva-Fernández; K Thevissen; W Vercoutere; E Villeneuve; D Aletaha; L Carmona; R Landewé; D van der Heijde; J W J Bijlsma; V Bykerk; H Canhão; A I Catrina; P Durez; C J Edwards; M D Mjaavatten; B F Leeb; B Losada; E M Martín-Mola; P Martinez-Osuna; C Montecucco; U Müller-Ladner; M Østergaard; B Sheane; R M Xavier; J Zochling; C Bombardier
Journal:  Ann Rheum Dis       Date:  2010-08-19       Impact factor: 19.103

Review 3.  Aspects of early arthritis. What determines the evolution of early undifferentiated arthritis and rheumatoid arthritis? An update from the Norfolk Arthritis Register.

Authors:  Deborah P M Symmons; Alan J Silman
Journal:  Arthritis Res Ther       Date:  2006       Impact factor: 5.156

4.  Early remission is associated with improved survival in patients with inflammatory polyarthritis: results from the Norfolk Arthritis Register.

Authors:  Carlo A Scirè; Mark Lunt; Tarnya Marshall; Deborah P M Symmons; Suzanne M M Verstappen
Journal:  Ann Rheum Dis       Date:  2013-06-07       Impact factor: 19.103

  4 in total

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